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    dhs-12 NAD(P)-binding protein [ Caenorhabditis elegans ]

    Gene ID: 177888, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dhs-12
    Official Full Name
    NAD(P)-binding protein
    Primary source
    WormBase:WBGene00000975
    Locus tag
    CELE_K08F4.9
    See related
    AllianceGenome:WB:WBGene00000975
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. Predicted to be active in cytoplasm. Orthologous to human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dhs-12 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (10145249..10146222)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene SH2 domain-containing protein Neighboring gene GPI transamidase component PIG-S

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of protein expression profiles during Caenorhabditis elegans development using two-dimensional difference gel electrophoresis. Tabuse Y, et al. Proteomics, 2005 Jul. PMID 15996007
    2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    5. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NAD(P)-binding protein
    NP_501850.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10145249..10146222
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069449.8 → NP_501850.1  NAD(P)-binding protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501850.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EG13
      Conserved Domains (2) summary
      cd05325
      Location:6 → 254
      carb_red_sniffer_like_SDR_c; carbonyl reductase sniffer-like, classical (c) SDRs
      pfam00106
      Location:4 → 217
      adh_short; short chain dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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