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    F27D9.7 Peptidase M12B domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185019, updated on 2-Nov-2024

    Summary

    Official Symbol
    F27D9.7
    Official Full Name
    Peptidase M12B domain-containing protein
    Primary source
    WormBase:WBGene00017865
    Locus tag
    CELE_F27D9.7
    See related
    AllianceGenome:WB:WBGene00017865
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in membrane. Orthologous to human ADAMDEC1 (ADAM like decysin 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See F27D9.7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (7667333..7670755, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene NADP-retinol dehydrogenase Neighboring gene ncRNA Neighboring gene VWFA domain-containing protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene PDZ domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metalloendopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in membrane protein ectodomain proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Peptidase M12B domain-containing protein
    NP_509295.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      7667333..7670755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076894.6NP_509295.3  Peptidase M12B domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19844
      Conserved Domains (2) summary
      pfam01421
      Location:56218
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      cl10507
      Location:246272
      Disintegrin