gst-42 putative maleylacetoacetate isomerase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: gst-42
Official Full Name: putative maleylacetoacetate isomerase
Primary source: WormBase:WBGene00001790
Locus tag: CELE_D1053.1
See related: AllianceGenome:WB:WBGene00001790
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables identical protein binding activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Is expressed in intestine. Orthologous to human GSTZ1 (glutathione S-transferase zeta 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gst-42 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 6

Sequence:: Chromosome: X; NC_003284.9 (11726264..11727936, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D1053.2 (e-PCR)
- UniSTS:316465

D1053.1 (e-PCR)
- UniSTS:319182

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables glutathione transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables isomerase activity	IEA Inferred from Electronic Annotation more info
enables maleylacetoacetate isomerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables maleylacetoacetate isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-phenylalanine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-phenylalanine catabolic process	IEA Inferred from Electronic Annotation more info
involved_in aromatic amino acid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in glutathione metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in tyrosine catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative maleylacetoacetate isomerase

NP_509962.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

11726264..11727936 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_077561.8 → NP_509962.1 putative maleylacetoacetate isomerase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_509962.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18938

Conserved Domains (3) summary

cd03191
Location:90 → 207

GST_C_Zeta; C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases

cd03042
Location:6 → 77

GST_N_Zeta; GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

TIGR01262
Location:7 → 211

maiA; maleylacetoacetate isomerase