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    F39H2.3 Aminomethyltransferase folate-binding domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172668, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F39H2.3
    Official Full Name
    Aminomethyltransferase folate-binding domain-containing protein
    Primary source
    WormBase:WBGene00009563
    Locus tag
    CELE_F39H2.3
    See related
    AllianceGenome:WB:WBGene00009563
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 74 and multiple mitochondrial dysfunctions syndrome 3. Orthologous to human IBA57 (iron-sulfur cluster assembly factor IBA57). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F39H2.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (8664976..8666497)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SPSAKWMRF-amide 3 Neighboring gene 5' exonuclease Apollo Neighboring gene Synaptonemal complex protein 3 Neighboring gene Nulp1-pending protein Neighboring gene Ovule protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in iron-sulfur cluster assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Aminomethyltransferase folate-binding domain-containing protein
    NP_492346.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8664976..8666497
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059945.7 → NP_492346.2  Aminomethyltransferase folate-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492346.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EE11
      Conserved Domains (1) summary
      COG0354
      Location:6 → 262
      YgfZ; Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version

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