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    unk-1 C3H1-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181059, updated on 9-Dec-2024

    Summary

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    Official Symbol
    unk-1
    Official Full Name
    C3H1-type domain-containing protein
    Primary source
    WormBase:WBGene00016407
    Locus tag
    CELE_C34D10.2
    See related
    AllianceGenome:WB:WBGene00016407
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Orthologous to several human genes including UNKL (unk like zinc finger). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See unk-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Sequence:
    Chromosome: X; NC_003284.9 (8014983..8026868)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene KfrA_N domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Truncated env protein Neighboring gene ncRNA Neighboring gene MSP domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reduced bone morphogenic protein signaling along the gut-neuron axis by heat shock factor promotes longevity. Arneaud SLB, et al. Aging Cell, 2022 Sep. PMID 35977034, Free PMC Article
    2. Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis. Crawford ED, et al. Cell Death Differ, 2012 Dec. PMID 22918439, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C3H1-type domain-containing protein
    NP_001263959.1
    • Confirmed by transcript evidence
    NP_001361954.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8014983..8026868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001375079.3 → NP_001361954.1  C3H1-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18437
      Conserved Domains (1) summary
      pfam18384
      Location:36 → 74
      zf_CCCH_5; Unkempt Zinc finger domain 1 (Znf1)

    2. NM_001277030.5 → NP_001263959.1  C3H1-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263959.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      L8E6Y3
    Nucleotide Protein
    Heading Accession and Version

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