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    Lbhd2 LBH domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 380787, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lbhd2provided by MGI
    Official Full Name
    LBH domain containing 2provided by MGI
    Primary source
    MGI:MGI:2685744
    See related
    Ensembl:ENSMUSG00000087075 AllianceGenome:MGI:2685744
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lbh2; Gm898; A230065H16Rik
    Summary
    Is expressed in forebrain. Orthologous to human LBHD2 (LBH domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 3.4), limb E14.5 (RPKM 2.7) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lbhd2 in Genome Data Viewer
    Location:
    12 F1; 12 60.98 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111368485..111378526)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111402049..111412092)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51960 Neighboring gene RIKEN cDNA A230087F16 gene Neighboring gene amnionless Neighboring gene CDC42 binding protein kinase beta Neighboring gene exocyst complex component 3-like 4 Neighboring gene tumor necrosis factor, alpha-induced protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Value-related learning in the olfactory bulb occurs through pathway-dependent perisomatic inhibition of mitral cells. Lindeman S, et al. PLoS Biol, 2024 Mar. PMID 38427708, Free PMC Article
    2. Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. Segal JP, et al. J Neurosci, 2005 Apr 20. PMID 15843621, Free PMC Article
    3. Generation and Characterization of a Cell Type-Specific, Inducible Cre-Driver Line to Study Olfactory Processing. Koldaeva A, et al. J Neurosci, 2021 Jul 28. PMID 34099512, Free PMC Article
    4. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    LBH domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101503.2 → NP_001094973.1  LBH domain-containing protein 2

      See identical proteins and their annotated locations for NP_001094973.1

      Status: VALIDATED

      Source sequence(s)
      AK038816, AW046934
      Consensus CDS
      CCDS49180.1
      UniProtKB/TrEMBL
      G3UW55
      Related
      ENSMUSP00000128648.2, ENSMUST00000150384.3
      Conserved Domains (1) summary
      pfam15317
      Location:26 → 61
      Lbh; Cardiac transcription factor regulator, Developmental protein

    2. NM_001358956.1 → NP_001345885.1  LBH domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AK038816, AW046934, BE649301
      Consensus CDS
      CCDS49180.1
      UniProtKB/TrEMBL
      G3UW55
      Conserved Domains (1) summary
      pfam15317
      Location:26 → 61
      Lbh; Cardiac transcription factor regulator, Developmental protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      111368485..111378526
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516048.3 → XP_006516111.1  LBH domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006516111.1

      UniProtKB/TrEMBL
      G3UW55
      Conserved Domains (1) summary
      pfam15317
      Location:26 → 61
      Lbh; Cardiac transcription factor regulator, Developmental protein

    2. XM_006516047.5 → XP_006516110.1  LBH domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006516110.1

      UniProtKB/TrEMBL
      G3UW55
      Conserved Domains (1) summary
      pfam15317
      Location:26 → 61
      Lbh; Cardiac transcription factor regulator, Developmental protein
    Nucleotide Protein Strain
    Heading Accession and Version

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