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    Ceacam12 CEA cell adhesion molecule 12 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361516, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ceacam12provided by RGD
    Official Full Name
    CEA cell adhesion molecule 12provided by RGD
    Primary source
    RGD:1306754
    See related
    EnsemblRapid:ENSRNOG00000042158 AllianceGenome:RGD:1306754
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Igfl3
    Summary
    Predicted to be involved in T cell activation and immune response. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Ceacam12 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (87344541..87351596)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (78216471..78223526)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79474809..79481865)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene carcinoembryonic antigen-related cell adhesion molecule 5-like Neighboring gene CEA cell adhesion molecule 11 Neighboring gene uncharacterized LOC134484888 Neighboring gene uncharacterized LOC134482893

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat. Frängsmyr L, et al. Tumour Biol, 1999 Sep-Oct. PMID 10436421
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    carcinoembryonic antigen-related cell adhesion molecule 3
    Names
    CEA-related cell adhesion molecule 12
    IGF-like family member 3
    IGF-like family member 3-like
    carcinoembryonic antigen-related cell adhesion molecule 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108474.1 → NP_001101944.1  carcinoembryonic antigen-related cell adhesion molecule 3

      See identical proteins and their annotated locations for NP_001101944.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/TrEMBL
      A0A8J8YCD1, B0BNJ2, D4A2T3
      Related
      ENSRNOP00000047257.5, ENSRNOT00000044927.6
      Conserved Domains (1) summary
      cd05774
      Location:36 → 140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      87344541..87351596
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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