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    UBAP2L ubiquitin associated protein 2 like [ Homo sapiens (human) ]

    Gene ID: 9898, updated on 10-Dec-2024

    Summary

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    Official Symbol
    UBAP2Lprovided by HGNC
    Official Full Name
    ubiquitin associated protein 2 likeprovided by HGNC
    Primary source
    HGNC:HGNC:29877
    See related
    Ensembl:ENSG00000143569 MIM:616472; AllianceGenome:HGNC:29877
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NICE4; NEDLBF; NICE-4
    Summary
    Enables RNA binding activity. Involved in binding activity of sperm to zona pellucida; positive regulation of stress granule assembly; and stress granule assembly. Acts upstream of or within hematopoietic stem cell homeostasis. Part of PcG protein complex. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis (RPKM 26.7), placenta (RPKM 21.3) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See UBAP2L in Genome Data Viewer
    Location:
    1q21.3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (154220172..154271510)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (153357369..153408720)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (154192648..154243986)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr1:154169885-154170114 Neighboring gene microRNA 190b Neighboring gene cilia and flagella associated protein 141 Neighboring gene chromosome 1 open reading frame 43 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:154192439-154193186 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:154193187-154193934 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:154205661-154206160 Neighboring gene small nucleolar RNA, H/ACA box 58B Neighboring gene ReSE screen-validated silencer GRCh37_chr1:154244721-154244861 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1775 Neighboring gene HCLS1 associated protein X-1 Neighboring gene small nucleolar RNA SNORD59

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Downregulation of ubiquitin-associated protein 2-like with a short hairpin RNA inhibits human glioma cell growth in vitro. Zhao B, et al. Int J Mol Med, 2015 Oct. PMID 26310274, Free PMC Article
    2. UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope. Liao Y, et al. J Cell Biol, 2024 Jul 1. PMID 38652117, Free PMC Article
    3. Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells. Lin S, et al. Bioengineered, 2021 Dec. PMID 34823423, Free PMC Article
    4. Large-scale tethered function assays identify factors that regulate mRNA stability and translation. Luo EC, et al. Nat Struct Mol Biol, 2020 Oct. PMID 32807991, Free PMC Article
    5. Ubiquitin Associated Protein 2-Like (UBAP2L) Overexpression in Patients with Hepatocellular Carcinoma and its Clinical Significance. Wang W, et al. Med Sci Monit, 2017 Oct 5. PMID 28981479, Free PMC Article

    See all (190) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope.
      Title: UBAP2L ensures homeostasis of nuclear pore complexes at the intact nuclear envelope.
    2. UBAP2L-dependent coupling of PLK1 localization and stability during mitosis.
      Title: UBAP2L-dependent coupling of PLK1 localization and stability during mitosis.
    3. UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.
      Title: UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase II and are the human orthologues of yeast Def1.
    4. Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells.
      Title: Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells.
    5. Molecular Insights into the Recruiting Between UCP2 and DDX5/UBAP2L in the Metabolic Plasticity of Non-Small-Cell Lung Cancer.
      Title: Molecular Insights into the Recruiting Between UCP2 and DDX5/UBAP2L in the Metabolic Plasticity of Non-Small-Cell Lung Cancer.
    6. UBAP2L arginine methylation by PRMT1 modulates stress granule assembly.
      Title: UBAP2L arginine methylation by PRMT1 modulates stress granule assembly.
    7. UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1.
      Title: UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1.
    8. Large-scale tethered function assays identify factors that regulate mRNA stability and translation.
      Title: Large-scale tethered function assays identify factors that regulate mRNA stability and translation.
    9. Patients with high UBAP2L expression had unfavorable prognosis and UBAP2L appears to play an important role in proliferation.
      Title: Clinical Significance of Ubiquitin-associated Protein 2-like in Patients With Uterine Cervical Cancer.
    10. UBAP2L plays an oncogenic role in HCC, and knockdown of its expression significantly inhibits HCC growth and metastasis, which may be related to the regulation of PI3K/AKT and P53 signaling pathways by UBAP2L.
      Title: Knockdown of Ubiquitin Associated Protein 2-Like (UBAP2L) Inhibits Growth and Metastasis of Hepatocellular Carcinoma.
    Submit: New GeneRIF Correction See all GeneRIFs (19)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Neurodevelopmental disorder with impaired language, behavioral abnormalities, and dysmorphic facies
    MedGen: C5882686 OMIM: 620494 GeneReviews: Not available
    		not available

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Protein interactions

    Protein Gene Interaction Pubs
    Pr55(Gag) gag Cellular biotinylated ubiquitin associated protein 2-like (UBAP2L) is incorporated into HIV-1 Gag virus-like particles PubMed
    Vpr vpr HIV-1 Vpr upregulates UBAP2L in HeLa cells within 12 hours of exposure PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ42300, KIAA0144

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in binding of sperm to zona pellucida IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in hematopoietic stem cell homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within hematopoietic stem cell homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of stress granule assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in stress granule assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of PcG protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasmic stress granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-associated protein 2-like
    Names
    RNA polymerase II degradation factor UBAP2L
    protein NICE-4

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127320.3 → NP_001120792.1  ubiquitin-associated protein 2-like isoform b

      See identical proteins and their annotated locations for NP_001120792.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the UTRs and 3' coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
      Source sequence(s)
      D63478, DC369803
      Consensus CDS
      CCDS44229.1
      UniProtKB/TrEMBL
      B4DZJ6
      Related
      ENSP00000345308.6, ENST00000343815.10
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    2. NM_001287815.1 → NP_001274744.1  ubiquitin-associated protein 2-like isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the UTRs, uses an alternate in-frame splice site in the central coding region, and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (c) is shorter and has a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AK303533, D63478, DC404293
      Consensus CDS
      CCDS72925.1
      UniProtKB/TrEMBL
      B4DZJ6
      Related
      ENSP00000478447.1, ENST00000613315.4
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:489 → 516
      DUF3697; Ubiquitin-associated protein 2

    3. NM_001287816.1 → NP_001274745.1  ubiquitin-associated protein 2-like isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate in-frame splice site in the central coding region, and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (d) is shorter and has a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AJ243670, AK302662, D63478, DC404293
      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    4. NM_001330730.1 → NP_001317659.1  ubiquitin-associated protein 2-like isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) uses an alternate in-frame splice junction and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (e) contains an alternate internal segment and has a shorter and distinct C-terminus compared to isoform a.
      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS81381.1
      UniProtKB/TrEMBL
      B4DYY5, F8W726
      Related
      ENSP00000271877.8, ENST00000271877.11
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    5. NM_001375612.1 → NP_001362541.1  ubiquitin-associated protein 2-like isoform f

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    6. NM_001375614.1 → NP_001362543.1  ubiquitin-associated protein 2-like isoform g

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Related
      ENSP00000389717.2, ENST00000437652.6
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    7. NM_001375615.1 → NP_001362544.1  ubiquitin-associated protein 2-like isoform h

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    8. NM_001375616.1 → NP_001362545.1  ubiquitin-associated protein 2-like isoform h

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    9. NM_001375617.1 → NP_001362546.1  ubiquitin-associated protein 2-like isoform i

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    10. NM_001375618.1 → NP_001362547.1  ubiquitin-associated protein 2-like isoform a

      Status: VALIDATED

      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS1063.1
      UniProtKB/Swiss-Prot
      B4E0U8, Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL2, Q9UGL3, Q9UGL4, Q9UGL5
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    11. NM_001375619.1 → NP_001362548.1  ubiquitin-associated protein 2-like isoform a

      Status: VALIDATED

      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS1063.1
      UniProtKB/Swiss-Prot
      B4E0U8, Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL2, Q9UGL3, Q9UGL4, Q9UGL5
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    12. NM_001375620.1 → NP_001362549.1  ubiquitin-associated protein 2-like isoform j

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    13. NM_001375621.1 → NP_001362550.1  ubiquitin-associated protein 2-like isoform j

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    14. NM_001375622.1 → NP_001362551.1  ubiquitin-associated protein 2-like isoform j

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    15. NM_001375623.1 → NP_001362552.1  ubiquitin-associated protein 2-like isoform k

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    16. NM_001375624.1 → NP_001362553.1  ubiquitin-associated protein 2-like isoform l

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    17. NM_001375625.1 → NP_001362554.1  ubiquitin-associated protein 2-like isoform e

      Status: VALIDATED

      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS81381.1
      UniProtKB/TrEMBL
      B4DYY5, F8W726
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    18. NM_001375626.1 → NP_001362555.1  ubiquitin-associated protein 2-like isoform m

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    19. NM_001375627.1 → NP_001362556.1  ubiquitin-associated protein 2-like isoform m

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    20. NM_001375628.1 → NP_001362557.1  ubiquitin-associated protein 2-like isoform n

      Status: VALIDATED

      Source sequence(s)
      AL590431
      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    21. NM_001375629.1 → NP_001362558.1  ubiquitin-associated protein 2-like isoform b

      Status: VALIDATED

      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS44229.1
      UniProtKB/TrEMBL
      B4DZJ6
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    22. NM_001375630.1 → NP_001362559.1  ubiquitin-associated protein 2-like isoform b

      Status: VALIDATED

      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS44229.1
      UniProtKB/TrEMBL
      B4DZJ6
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    23. NM_001375631.1 → NP_001362560.1  ubiquitin-associated protein 2-like isoform b

      Status: VALIDATED

      Source sequence(s)
      AL590431
      Consensus CDS
      CCDS44229.1
      UniProtKB/TrEMBL
      B4DZJ6
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    24. NM_014847.4 → NP_055662.3  ubiquitin-associated protein 2-like isoform a

      See identical proteins and their annotated locations for NP_055662.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      BC003170, D63478, DC404293
      Consensus CDS
      CCDS1063.1
      UniProtKB/Swiss-Prot
      B4E0U8, Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL2, Q9UGL3, Q9UGL4, Q9UGL5
      UniProtKB/TrEMBL
      Q5VU79
      Related
      ENSP00000389445.1, ENST00000428931.6
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      154220172..154271510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047435869.1 → XP_047291825.1  ubiquitin-associated protein 2-like isoform X7

      UniProtKB/TrEMBL
      B4DYY5

    2. XM_047435875.1 → XP_047291831.1  ubiquitin-associated protein 2-like isoform X8

      UniProtKB/TrEMBL
      B4DYY5

    3. XM_047435827.1 → XP_047291783.1  ubiquitin-associated protein 2-like isoform X2

      UniProtKB/TrEMBL
      Q5VU79

    4. XM_005245668.5 → XP_005245725.1  ubiquitin-associated protein 2-like isoform X5

      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    5. XM_005245669.5 → XP_005245726.1  ubiquitin-associated protein 2-like isoform X6

      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    6. XM_047435866.1 → XP_047291822.1  ubiquitin-associated protein 2-like isoform X7

      UniProtKB/TrEMBL
      B4DYY5

    7. XM_017002982.3 → XP_016858471.1  ubiquitin-associated protein 2-like isoform X8

      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    8. XM_005245672.5 → XP_005245729.1  ubiquitin-associated protein 2-like isoform X12

      UniProtKB/TrEMBL
      B4DYY5
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:496 → 523
      DUF3697; Ubiquitin-associated protein 2

    9. XM_005245667.5 → XP_005245724.1  ubiquitin-associated protein 2-like isoform X3

      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    10. XM_011510215.4 → XP_011508517.1  ubiquitin-associated protein 2-like isoform X1

      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    11. XM_005245673.5 → XP_005245730.1  ubiquitin-associated protein 2-like isoform X13

      UniProtKB/TrEMBL
      A0AA34QVE6, B4DZJ6
      Related
      ENSP00000516761.1, ENST00000707139.1
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    12. XM_047435856.1 → XP_047291812.1  ubiquitin-associated protein 2-like isoform X5

      UniProtKB/TrEMBL
      B4DYY5

    13. XM_047435859.1 → XP_047291815.1  ubiquitin-associated protein 2-like isoform X6

      UniProtKB/TrEMBL
      B4DYY5

    14. XM_047435876.1 → XP_047291832.1  ubiquitin-associated protein 2-like isoform X9

      UniProtKB/TrEMBL
      B4DYY5

    15. XM_047435828.1 → XP_047291784.1  ubiquitin-associated protein 2-like isoform X3

      UniProtKB/TrEMBL
      Q5VU79

    16. XM_017002972.3 → XP_016858461.1  ubiquitin-associated protein 2-like isoform X1

      UniProtKB/TrEMBL
      Q5VU79
      Conserved Domains (2) summary
      cd14277
      Location:50 → 87
      UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
      pfam12478
      Location:507 → 534
      DUF3697; Ubiquitin-associated protein 2

    17. XM_047435844.1 → XP_047291800.1  ubiquitin-associated protein 2-like isoform X4

      UniProtKB/TrEMBL
      Q5VU79

    18. XM_047435898.1 → XP_047291854.1  ubiquitin-associated protein 2-like isoform X13

      UniProtKB/TrEMBL
      A0AA34QVE6, B4DZJ6

    19. XM_047435877.1 → XP_047291833.1  ubiquitin-associated protein 2-like isoform X10

      UniProtKB/TrEMBL
      B4DYY5, F8W726

    20. XM_047435868.1 → XP_047291824.1  ubiquitin-associated protein 2-like isoform X7

      UniProtKB/TrEMBL
      B4DYY5

    21. XM_047435887.1 → XP_047291843.1  ubiquitin-associated protein 2-like isoform X11

      UniProtKB/TrEMBL
      B4DYY5

    22. XM_047435874.1 → XP_047291830.1  ubiquitin-associated protein 2-like isoform X8

      UniProtKB/TrEMBL
      B4DYY5

    23. XM_047435896.1 → XP_047291852.1  ubiquitin-associated protein 2-like isoform X12

      UniProtKB/TrEMBL
      B4DYY5

    24. XM_047435834.1 → XP_047291790.1  ubiquitin-associated protein 2-like isoform X3

      UniProtKB/TrEMBL
      Q5VU79

    25. XM_047435820.1 → XP_047291776.1  ubiquitin-associated protein 2-like isoform X1

      UniProtKB/TrEMBL
      Q5VU79

    26. XM_047435852.1 → XP_047291808.1  ubiquitin-associated protein 2-like isoform X4

      UniProtKB/TrEMBL
      Q5VU79

    27. XM_047435824.1 → XP_047291780.1  ubiquitin-associated protein 2-like isoform X2

      UniProtKB/TrEMBL
      Q5VU79

    28. XM_047435905.1 → XP_047291861.1  ubiquitin-associated protein 2-like isoform X13

      UniProtKB/TrEMBL
      A0AA34QVE6, B4DZJ6

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      153357369..153408720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054339904.1 → XP_054195879.1  ubiquitin-associated protein 2-like isoform X7

      UniProtKB/TrEMBL
      B4DYY5

    2. XM_054339907.1 → XP_054195882.1  ubiquitin-associated protein 2-like isoform X8

      UniProtKB/TrEMBL
      B4DYY5

    3. XM_054339892.1 → XP_054195867.1  ubiquitin-associated protein 2-like isoform X2

      UniProtKB/TrEMBL
      Q5VU79

    4. XM_054339899.1 → XP_054195874.1  ubiquitin-associated protein 2-like isoform X5

      UniProtKB/TrEMBL
      B4DYY5

    5. XM_054339901.1 → XP_054195876.1  ubiquitin-associated protein 2-like isoform X6

      UniProtKB/TrEMBL
      B4DYY5

    6. XM_054339902.1 → XP_054195877.1  ubiquitin-associated protein 2-like isoform X7

      UniProtKB/TrEMBL
      B4DYY5

    7. XM_054339905.1 → XP_054195880.1  ubiquitin-associated protein 2-like isoform X8

      UniProtKB/TrEMBL
      B4DYY5

    8. XM_054339911.1 → XP_054195886.1  ubiquitin-associated protein 2-like isoform X12

      UniProtKB/TrEMBL
      B4DYY5

    9. XM_054339894.1 → XP_054195869.1  ubiquitin-associated protein 2-like isoform X3

      UniProtKB/TrEMBL
      Q5VU79

    10. XM_054339889.1 → XP_054195864.1  ubiquitin-associated protein 2-like isoform X1

      UniProtKB/TrEMBL
      Q5VU79

    11. XM_054339915.1 → XP_054195890.1  ubiquitin-associated protein 2-like isoform X13

      UniProtKB/TrEMBL
      A0AA34QVE6, B4DZJ6

    12. XM_054339898.1 → XP_054195873.1  ubiquitin-associated protein 2-like isoform X5

      UniProtKB/TrEMBL
      B4DYY5

    13. XM_054339900.1 → XP_054195875.1  ubiquitin-associated protein 2-like isoform X6

      UniProtKB/TrEMBL
      B4DYY5

    14. XM_054339908.1 → XP_054195883.1  ubiquitin-associated protein 2-like isoform X9

      UniProtKB/TrEMBL
      B4DYY5

    15. XM_054339893.1 → XP_054195868.1  ubiquitin-associated protein 2-like isoform X3

      UniProtKB/TrEMBL
      Q5VU79

    16. XM_054339888.1 → XP_054195863.1  ubiquitin-associated protein 2-like isoform X1

      UniProtKB/TrEMBL
      Q5VU79

    17. XM_054339896.1 → XP_054195871.1  ubiquitin-associated protein 2-like isoform X4

      UniProtKB/TrEMBL
      Q5VU79

    18. XM_054339913.1 → XP_054195888.1  ubiquitin-associated protein 2-like isoform X13

      UniProtKB/TrEMBL
      A0AA34QVE6, B4DZJ6

    19. XM_054339909.1 → XP_054195884.1  ubiquitin-associated protein 2-like isoform X10

      UniProtKB/TrEMBL
      B4DYY5, F8W726

    20. XM_054339903.1 → XP_054195878.1  ubiquitin-associated protein 2-like isoform X7

      UniProtKB/TrEMBL
      B4DYY5

    21. XM_054339910.1 → XP_054195885.1  ubiquitin-associated protein 2-like isoform X11

      UniProtKB/TrEMBL
      B4DYY5

    22. XM_054339906.1 → XP_054195881.1  ubiquitin-associated protein 2-like isoform X8

      UniProtKB/TrEMBL
      B4DYY5

    23. XM_054339912.1 → XP_054195887.1  ubiquitin-associated protein 2-like isoform X12

      UniProtKB/TrEMBL
      B4DYY5

    24. XM_054339895.1 → XP_054195870.1  ubiquitin-associated protein 2-like isoform X3

      UniProtKB/TrEMBL
      Q5VU79

    25. XM_054339890.1 → XP_054195865.1  ubiquitin-associated protein 2-like isoform X1

      UniProtKB/TrEMBL
      Q5VU79

    26. XM_054339897.1 → XP_054195872.1  ubiquitin-associated protein 2-like isoform X4

      UniProtKB/TrEMBL
      Q5VU79

    27. XM_054339891.1 → XP_054195866.1  ubiquitin-associated protein 2-like isoform X2

      UniProtKB/TrEMBL
      Q5VU79

    28. XM_054339914.1 → XP_054195889.1  ubiquitin-associated protein 2-like isoform X13

      UniProtKB/TrEMBL
      A0AA34QVE6, B4DZJ6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q14157.2 GenPept UniProtKB/Swiss-Prot:Q14157

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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