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    Tango9 Transport and Golgi organization 9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41450, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tango9provided by FlyBase
    Official Full Name
    Transport and Golgi organization 9provided by FlyBase
    Primary source
    FLYBASE:FBgn0260744
    Locus tag
    Dmel_CG10007
    See related
    AllianceGenome:FB:FBgn0260744
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    87A7-9/5; anon-87Ad; CG10007; Dmel\CG10007; TANGO9
    Summary
    Predicted to enable antiporter activity and nucleotide-sugar transmembrane transporter activity. Involved in protein secretion. Located in Golgi apparatus. Is expressed in adult head and adult heart. Orthologous to human SLC35F6 (solute carrier family 35 member F6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tango9 in Genome Data Viewer
    Location:
    87A4-87A4; 3-51 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11971007..11974910, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7798812..7800632, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Heat shock protein 70 Ab Neighboring gene uncharacterized protein Neighboring gene aurora A Neighboring gene uncharacterized protein Neighboring gene Glutamate Carrier 1 Neighboring gene Glutamate Carrier 2 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44135

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Glover DM, et al. Cell, 1995 Apr 7. PMID 7720077
    2. mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Behm-Ansmant I, et al. Genes Dev, 2006 Jul 15. PMID 16815998, Free PMC Article
    3. Promoter-Proximal Chromatin Domain Insulator Protein BEAF Mediates Local and Long-Range Communication with a Transcription Factor and Directly Activates a Housekeeping Promoter in Drosophila. Dong Y, et al. Genetics, 2020 May. PMID 32179582, Free PMC Article
    4. Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body. Juhász G, et al. Cell Death Differ, 2007 Jun. PMID 17363962, Free PMC Article
    5. The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. Gurudatta BV, et al. Dev Biol, 2012 Sep 1. PMID 22743648, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables nucleotide-sugar transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in nucleotide-sugar transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein secretion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transport and golgi organization 9
    Names
    CG10007-PA
    CG10007-PB
    Tango9-PA
    Tango9-PB
    anon-87Ad

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11971007..11974910 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001316533.1 → NP_001303462.1  transport and golgi organization 9, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGF5

    2. NM_141879.3 → NP_650136.1  transport and golgi organization 9, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650136.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VGF5
      Related
      FBpp0081982
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VGF5 Q9VGF5

    Gene LinkOut

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