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    hng1 hinge1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37412, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hng1provided by FlyBase
    Official Full Name
    hinge1provided by FlyBase
    Primary source
    FLYBASE:FBgn0034599
    Locus tag
    Dmel_CG9437
    See related
    AllianceGenome:FB:FBgn0034599
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9437; Dmel\CG9437
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in organism; wing disc; and wing hinge. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See hng1 in Genome Data Viewer
    Location:
    57C7-57C7; 2-93 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21168930..21170010)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17056435..17057515)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Tryptophan-CCA 2-4 Neighboring gene Insulator su(Hw) mRNA adaptor Neighboring gene Like Sm 1 Neighboring gene Xeroderma pigmentosum D Neighboring gene Punch Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. Shukla V, et al. G3 (Bethesda), 2018 May 31. PMID 29669801, Free PMC Article
    2. The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Bhaskar V, et al. Gene, 2002 Oct 16. PMID 12459265
    3. Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge. Shukla V, et al. Genetics, 2014 Feb. PMID 24336749, Free PMC Article
    4. Identification of atlastin genetic modifiers in a model of hereditary spastic paraplegia in Drosophila. Candia N, et al. Hum Genet, 2023 Aug. PMID 37368047
    5. The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. Kwong PN, et al. J Biol Chem, 2015 Dec 11. PMID 26483546, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hinge1
    Names
    CG9437-PA
    hng1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21168930..21170010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137714.4 → NP_611558.2  hinge1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611558.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AQG0, C0MK19, Q9W2K3
      Related
      FBpp0071502
      Conserved Domains (2) summary
      smart00595
      Location:15 → 98
      MADF; subfamily of SANT domain
      pfam02944
      Location:264 → 298
      BESS; BESS motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95R85 Q95R85
    Q9W2K3 Q9W2K3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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