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    CG17597 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35140, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17597provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032715
    Locus tag
    Dmel_CG17597
    See related
    AllianceGenome:FB:FBgn0032715
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17597; SCP2
    Summary
    Predicted to enable acetyl-CoA C-acyltransferase activity. Predicted to be active in peroxisome. Is expressed in adult head; adult heart; embryonic Malpighian tubule; embryonic/larval midgut; and organism. Orthologous to human SCP2 (sterol carrier protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17597 in Genome Data Viewer
    Location:
    37B1-37B1; 2-54 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18829012..18831153, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18829012..18831153, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene UDP-glycosyltransferase family 36 member F1 Neighboring gene UDP-glycosyltransferase family 36 member D1 Neighboring gene UDP-glycosyltransferase family 36 member E1 Neighboring gene Sterol carrier protein X-related thiolase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel Drosophila model of myotonic dystrophy type 1: phenotypic characterization and genome-wide view of altered gene expression. Picchio L, et al. Hum Mol Genet, 2013 Jul 15. PMID 23525904
    2. Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila. Gallach M, et al. Genome Biol Evol, 2010. PMID 21037198, Free PMC Article
    3. Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Palanker L, et al. Cell Metab, 2009 Mar. PMID 19254568, Free PMC Article
    4. Chronic dysfunction of Stromal interaction molecule by pulsed RNAi induction in fat tissue impairs organismal energy homeostasis in Drosophila. Xu Y, et al. Sci Rep, 2019 May 6. PMID 31061470, Free PMC Article
    5. Relish-facilitated lncRNA-CR11538 suppresses Drosophila Imd immune response and maintains immune homeostasis via decoying Relish away from antimicrobial peptide promoters. Huang Y, et al. Dev Comp Immunol, 2024 Feb. PMID 37956726

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acetyl-CoA C-acyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisome ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17597-PA
    CG17597-PB
    NP_001286066.1
    NP_609912.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18829012..18831153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299137.1 → NP_001286066.1  uncharacterized protein Dmel_CG17597, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286066.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q24507, Q95TG8, Q9VJ44
      Conserved Domains (2) summary
      PRK08256
      Location:5 → 396
      PRK08256; lipid-transfer protein; Provisional
      cd00829
      Location:9 → 395
      SCP-x_thiolase; Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal ...

    2. NM_136068.4 → NP_609912.1  uncharacterized protein Dmel_CG17597, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609912.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q24507, Q95TG8, Q9VJ44
      Related
      FBpp0080666
      Conserved Domains (2) summary
      PRK08256
      Location:5 → 396
      PRK08256; lipid-transfer protein; Provisional
      cd00829
      Location:9 → 395
      SCP-x_thiolase; Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJ44 Q9VJ44

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