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    CG31689 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326154, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31689provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031449
    Locus tag
    Dmel_CG31689
    See related
    AllianceGenome:FB:FBgn0031449
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9892; DmCG31689; Dmel\CG31689
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; embryonic small intestine; gut section; and hindgut proper primordium. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1) and ABCG4 (ATP binding cassette subfamily G member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31689 in Genome Data Viewer
    Location:
    23A3-23A3; 2-7 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2725674..2739830)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2725674..2739830)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 23a Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 1 Neighboring gene TBP-related factor 5 Neighboring gene mir-4914 stem loop Neighboring gene uncharacterized protein Neighboring gene Hepatocyte growth factor regulated tyrosine kinase substrate Neighboring gene Cwc25 Neighboring gene Phosphoglycerate kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The polarity protein Dlg5 regulates collective cell migration during Drosophila oogenesis. Luo J, et al. PLoS One, 2019. PMID 31856229, Free PMC Article
    2. Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila. Sharma A, et al. Sci Rep, 2020 Nov 5. PMID 33154387, Free PMC Article
    3. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
    4. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article
    5. A genome-wide RNAi screen identifies MASK as a positive regulator of cytokine receptor stability. Fisher KH, et al. J Cell Sci, 2018 Jul 6. PMID 29848658, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31689-PA
    CG31689-PB
    CG31689-PC
    CG31689-PD
    CG31689-PE
    CG31689-PF
    CG31689-PG
    CG31689-PH
    NP_001259951.1
    NP_001259952.1
    NP_001259953.1
    NP_001259954.1
    NP_608703.2
    NP_722827.1
    NP_722828.1
    NP_722829.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2725674..2739830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273025.1 → NP_001259954.1  uncharacterized protein Dmel_CG31689, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259954.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBX3, Q8T998
      Conserved Domains (3) summary
      cd03213
      Location:26 → 239
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:15 → 622
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:355 → 558
      ABC2_membrane; ABC-2 type transporter

    2. NM_164495.2 → NP_722829.1  uncharacterized protein Dmel_CG31689, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722829.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Related
      FBpp0077390
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter

    3. NM_164493.2 → NP_722827.1  uncharacterized protein Dmel_CG31689, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722827.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Related
      FBpp0077391
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter

    4. NM_134859.3 → NP_608703.2  uncharacterized protein Dmel_CG31689, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608703.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Related
      FBpp0077389
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter

    5. NM_001273023.1 → NP_001259952.1  uncharacterized protein Dmel_CG31689, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259952.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter

    6. NM_164494.2 → NP_722828.1  uncharacterized protein Dmel_CG31689, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722828.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Related
      FBpp0077392
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter

    7. NM_001273022.1 → NP_001259951.1  uncharacterized protein Dmel_CG31689, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259951.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter

    8. NM_001273024.1 → NP_001259953.1  uncharacterized protein Dmel_CG31689, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259953.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T998, Q9VQF1
      Conserved Domains (3) summary
      cd03213
      Location:12 → 230
      ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
      TIGR00955
      Location:28 → 613
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:346 → 549
      ABC2_membrane; ABC-2 type transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PBX3 M9PBX3
    Q8T998 Q8T998
    Q9VQF1 Q9VQF1

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