Dhdds Dehydrodolichyl diphosphate synthase subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Dhddsprovided by FlyBase
Official Full Name: Dehydrodolichyl diphosphate synthase subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0029980
Locus tag: Dmel_CG10778
See related: AllianceGenome:FB:FBgn0029980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG10778; DHDDS; Dmel\CG10778
Summary: Predicted to enable transferase activity, transferring alkyl or aryl (other than methyl) groups. Predicted to contribute to dehydrodolichyl diphosphate synthase activity. Predicted to be involved in polyprenol biosynthetic process. Predicted to be part of dehydrodolichyl diphosphate synthase complex. Predicted to be active in endoplasmic reticulum. Is expressed in adult head; embryonic/larval midgut; and organism. Used to study retinitis pigmentosa 59. Human ortholog(s) of this gene implicated in developmental delay and seizures with or without movement abnormalities and retinitis pigmentosa 59. Orthologous to human DHDDS (dehydrodolichyl diphosphate synthase subunit). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (7931745..7933351, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (7825778..7827384, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Function	Evidence Code	Pubs
contributes_to dehydrodolichyl diphosphate synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity, transferring alkyl or aryl (other than methyl) groups	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in polyprenol biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of dehydrodolichyl diphosphate synthase complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

Names: CG10778-PA; CG10778-PB; Dhdds-PA; Dhdds-PB; dehydrodolichyl diphosphate synthase; prenyltransferase

NP_001259316.1

NP_572425.1

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The following sections contain reference sequences that belong to a specific genome build. Explain