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    CG7766 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31839, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7766provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030087
    Locus tag
    Dmel_CG7766
    See related
    AllianceGenome:FB:FBgn0030087
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7766
    Summary
    Predicted to enable calmodulin binding activity. Predicted to be involved in positive regulation of glycogen catabolic process. Predicted to be part of phosphorylase kinase complex. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut; embryonic/larval midgut primordium; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in glycogen storage disease; glycogen storage disease IXa; and glycogen storage disease IXd. Orthologous to human PHKA1 (phosphorylase kinase regulatory subunit alpha 1) and PHKA2 (phosphorylase kinase regulatory subunit alpha 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7766 in Genome Data Viewer
    Location:
    8C8-8C9; 1-26 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9093612..9103739, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8987645..8997772, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Chaperonin containing TCP1 subunit 2 Neighboring gene mir-13b-2 stem loop Neighboring gene Bx42 Neighboring gene ADP-ribosylation factor related protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Larschan E, et al. Mol Cell, 2007 Oct 12. PMID 17936709
    2. Parallel and population-specific gene regulatory evolution in cold-adapted fly populations. Huang Y, et al. Genetics, 2021 Jul 14. PMID 33989401, Free PMC Article
    3. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Wang CI, et al. Nat Struct Mol Biol, 2013 Feb. PMID 23295261, Free PMC Article
    4. Drosophila melanogaster males respond differently at the behavioural and genome-wide levels to Drosophila melanogaster and Drosophila simulans females. Ellis LL, et al. J Evol Biol, 2009 Nov. PMID 19765174
    5. An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance. Lebo DPV, et al. G3 (Bethesda), 2021 Feb 9. PMID 33693600, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycogen metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of glycogen catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of phosphorylase kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7766-PA
    CG7766-PB
    CG7766-PC
    CG7766-PD
    CG7766-PG
    CG7766-PH
    CG7766-PI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9093612..9103739 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298107.1 → NP_001285036.1  uncharacterized protein Dmel_CG7766, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285036.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQI4, X2JJ32
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15

    2. NM_176716.4 → NP_788889.2  uncharacterized protein Dmel_CG7766, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788889.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQI4
      Related
      FBpp0071287
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15

    3. NM_001258658.2 → NP_001245587.1  uncharacterized protein Dmel_CG7766, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245587.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQI4, M9NGW5
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15

    4. NM_001258659.2 → NP_001245588.1  uncharacterized protein Dmel_CG7766, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245588.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQI4, M9NDS5
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15

    5. NM_001144708.3 → NP_001138180.1  uncharacterized protein Dmel_CG7766, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138180.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z134, D0IQI4
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15

    6. NM_132297.6 → NP_572525.3  uncharacterized protein Dmel_CG7766, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572525.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B60, Q95TZ6, Q9W391
      UniProtKB/TrEMBL
      D0IQI4
      Related
      FBpp0071286
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15

    7. NM_001144707.3 → NP_001138179.1  uncharacterized protein Dmel_CG7766, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138179.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0IQI4, Q6IDE0
      Conserved Domains (1) summary
      pfam00723
      Location:8 → 439
      Glyco_hydro_15; Glycosyl hydrolases family 15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7Z134 B7Z134
    M9NDS5 M9NDS5
    M9NGW5 M9NGW5
    Q6IDE0 Q6IDE0
    Q9W391.2 Q9W391
    X2JJ32 X2JJ32

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