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    CG5708 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34361, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5708provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032196
    Locus tag
    Dmel_CG5708
    See related
    AllianceGenome:FB:FBgn0032196
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5708
    Summary
    Predicted to be involved in leg disc development. Predicted to be located in nucleus. Is expressed in wing hinge primordium and wing pouch. Orthologous to human LMO4 (LIM domain only 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5708 in Genome Data Viewer
    Location:
    31B1-31B1; 2-40 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10224457..10226808, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10224457..10226808, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Proteasome alpha6 subunit Neighboring gene Bcs1 chaperone Neighboring gene ovaries absent Neighboring gene eukaryotic translation elongation factor 1 delta

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and Lim1 regulate distal leg development. Pueyo JI, et al. Development, 2004 Jul. PMID 15175252
    2. An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP. Fiedler M, et al. Elife, 2015 Aug 27. PMID 26312500, Free PMC Article
    3. The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis. She M, et al. Front Cardiovasc Med, 2021. PMID 33681304, Free PMC Article
    4. Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover. Huang S, et al. PLoS Biol, 2013 Nov. PMID 24302888, Free PMC Article
    5. Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome. Grimberg KB, et al. Mol Cell Biol, 2011 Feb. PMID 21149573, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in leg disc development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5708-PA
    CG5708-PB
    CG5708-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10224457..10226808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298870.1 → NP_001285799.1  uncharacterized protein Dmel_CG5708, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285799.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL21
      Conserved Domains (2) summary
      cd09386
      Location:78 → 132
      LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
      cl02475
      Location:142 → 212
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    2. NM_164893.2 → NP_723534.1  uncharacterized protein Dmel_CG5708, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723534.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL21
      Related
      FBpp0079546
      Conserved Domains (2) summary
      cd09386
      Location:78 → 132
      LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
      cl02475
      Location:142 → 212
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    3. NM_135515.2 → NP_609359.1  uncharacterized protein Dmel_CG5708, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609359.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL21
      Related
      FBpp0079545
      Conserved Domains (2) summary
      cd09386
      Location:78 → 132
      LIM1_LMO4; The first LIM domain of LMO4 (LIM domain only protein 4)
      cl02475
      Location:142 → 212
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VL21 Q9VL21

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