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    brv3 brivido-3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31246, updated on 9-Dec-2024

    Summary

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    Official Symbol
    brv3provided by FlyBase
    Official Full Name
    brivido-3provided by FlyBase
    Primary source
    FLYBASE:FBgn0040333
    Locus tag
    Dmel_CG13762
    See related
    AllianceGenome:FB:FBgn0040333
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Brivido 3; Brivido3; Brv-3; Brv3; CG13762; CT33244; Dmel\CG13762; EG:BACR7C10.7
    Summary
    Predicted to enable calcium channel activity. Involved in response to cold. Predicted to be active in membrane. Orthologous to human PKD1L3 (polycystin 1 like 3, transient receptor potential channel interacting). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See brv3 in Genome Data Viewer
    Location:
    3A8-3A8; 1-1 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2622069..2624575, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2516102..2518608, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit g1 Neighboring gene Tetraspanin 3A Neighboring gene Phosphatidylinositol 4-kinase III alpha Neighboring gene seipin Neighboring gene shaggy Neighboring gene long non-coding RNA:CR45197

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The coding of temperature in the Drosophila brain. Gallio M, et al. Cell, 2011 Feb 18. PMID 21335241, Free PMC Article
    2. Temperature sensation in Drosophila. Barbagallo B, et al. Curr Opin Neurobiol, 2015 Oct. PMID 25616212, Free PMC Article
    3. Feeling Hot and Cold: Thermal Sensation in Drosophila. Li K, et al. Neurosci Bull, 2017 Jun. PMID 27995563, Free PMC Article
    4. Thermotaxis, circadian rhythms, and TRP channels in Drosophila. Bellemer A. Temperature (Austin), 2015 Apr-Jun. PMID 27227026, Free PMC Article
    5. Transient receptor potential channels: current perspectives on evolution, structure, function and nomenclature. Himmel NJ, et al. Proc Biol Sci, 2020 Aug 26. PMID 32842926, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium ion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in detection of mechanical stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    brivido-3
    Names
    Brivido-3
    CG13762-PB
    CG13762-PC
    brv3-PB
    brv3-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2622069..2624575 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130657.3 → NP_570013.3  brivido-3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570013.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      H0RNK9, Q9W4X5
      Conserved Domains (1) summary
      pfam08016
      Location:170 → 595
      PKD_channel; Polycystin cation channel

    2. NM_001297902.1 → NP_001284831.1  brivido-3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284831.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U1K9, X2JI61
      Conserved Domains (1) summary
      pfam08016
      Location:170 → 595
      PKD_channel; Polycystin cation channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U0S7 Q5U0S7
    Q9U1K9 Q9U1K9
    Q9W4X5 Q9W4X5
    X2JI61 X2JI61

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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