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    CG9518 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32416, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9518provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030590
    Locus tag
    Dmel_CG9518
    See related
    AllianceGenome:FB:FBgn0030590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dm GMCzeta1; Dmel\CG9518
    Summary
    Predicted to enable oxidoreductase activity. Involved in response to endoplasmic reticulum stress. Is expressed in embryonic dorsal epidermis; embryonic proventriculus inner layer; embryonic ventral epidermis; and gut section. Orthologous to human CHDH (choline dehydrogenase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9518 in Genome Data Viewer
    Location:
    12F6-12F7; 1-49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (14862989..14871181, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14757022..14765214, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Flotillin 2 Neighboring gene long non-coding RNA:CR46391 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on CH-OH group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ecdysteroid metabolic process IGC
    Inferred from Genomic Context
    more info
    		 PubMed 
    involved_in ecdysteroid metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in response to endoplasmic reticulum stress HMP PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9518-PA
    CG9518-PB
    CG9518-PC
    NP_001285249.1
    NP_001285250.1
    NP_572979.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      14862989..14871181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132751.2 → NP_572979.1  uncharacterized protein Dmel_CG9518, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572979.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NR10, Q9VY08
      Related
      FBpp0073800
      Conserved Domains (3) summary
      PRK02106
      Location:56 → 614
      PRK02106; choline dehydrogenase; Validated
      pfam05199
      Location:465 → 608
      GMC_oxred_C; GMC oxidoreductase
      cl21454
      Location:128 → 351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. NM_001298320.1 → NP_001285249.1  uncharacterized protein Dmel_CG9518, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285249.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NR10, Q9VY08
      Conserved Domains (3) summary
      PRK02106
      Location:56 → 614
      PRK02106; choline dehydrogenase; Validated
      pfam05199
      Location:465 → 608
      GMC_oxred_C; GMC oxidoreductase
      cl21454
      Location:128 → 351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. NM_001298321.1 → NP_001285250.1  uncharacterized protein Dmel_CG9518, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285250.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NR10, Q9VY08
      Conserved Domains (3) summary
      PRK02106
      Location:56 → 614
      PRK02106; choline dehydrogenase; Validated
      pfam05199
      Location:465 → 608
      GMC_oxred_C; GMC oxidoreductase
      cl21454
      Location:128 → 351
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NR10 Q6NR10
    Q9VY08 Q9VY08

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