CCKLR-17D3 Cholecystokinin-like receptor at 17D3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CCKLR-17D3provided by FlyBase
Official Full Name: Cholecystokinin-like receptor at 17D3provided by FlyBase
Primary source: FLYBASE:FBgn0030954
Locus tag: Dmel_CG32540
See related: AllianceGenome:FB:FBgn0030954
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0131005.21; anon-WO0170980.64; anon-WO0170980.65; CCKLR-17D3-R; CCKLR-D3; CG32540; CG6861; CG6881; CG6894; Dmel\CG32540; DSK-R1; DskR-1; SK-R
Summary: Predicted to enable neuropeptide receptor activity. Involved in adult locomotory behavior. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; and panic disorder. Orthologous to several human genes including CCKAR (cholecystokinin A receptor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (18764483..18774027, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (18658516..18668060, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables gastrin receptor activity	IEA Inferred from Electronic Annotation more info
enables neuropeptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables neuropeptide receptor activity	ISM Inferred from Sequence Model more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway	ISM Inferred from Sequence Model more info	PubMed
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in adult locomotory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuropeptide signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISM Inferred from Sequence Model more info	PubMed
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: CCK-like receptor at 17D3; CCKLR-17D3-PB; CG32540-PB; DSK-receptor2; sulfakinin receptor

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The following sections contain reference sequences that belong to a specific genome build. Explain