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    CG9643 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33504, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9643provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031485
    Locus tag
    Dmel_CG9643
    See related
    AllianceGenome:FB:FBgn0031485
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9643; METTL10
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be active in cytoplasm. Is expressed in embryonic/larval midgut and organism. Orthologous to human EEF1AKMT2 (EEF1A lysine methyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9643 in Genome Data Viewer
    Location:
    23C4-23C4; 2-8 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2978411..2979288, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2978411..2979288, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene gamma-Tubulin at 23C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chromodomain-helicase-DNA-binding protein 1 Neighboring gene Bem46 Neighboring gene okra

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo. Konev AY, et al. Science, 2007 Aug 24. PMID 17717186, Free PMC Article
    2. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
    3. Evidence for large domains of similarly expressed genes in the Drosophila genome. Spellman PT, et al. J Biol, 2002. PMID 12144710, Free PMC Article
    4. gammaTub23C interacts genetically with brahma chromatin-remodeling complexes in Drosophila melanogaster. Vázquez M, et al. Genetics, 2008 Oct. PMID 18780727, Free PMC Article
    5. Network analyses reveal novel aspects of ALS pathogenesis. Sanhueza M, et al. PLoS Genet, 2015 Mar. PMID 25826266, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9643-PA
    CG9643-PB
    NP_001285572.1
    NP_608733.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2978411..2979288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298643.1 → NP_001285572.1  uncharacterized protein Dmel_CG9643, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285572.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQJ8
      Conserved Domains (1) summary
      pfam12847
      Location:59 → 173
      Methyltransf_18; Methyltransferase domain

    2. NM_134889.3 → NP_608733.1  uncharacterized protein Dmel_CG9643, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608733.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQJ8
      Related
      FBpp0077359
      Conserved Domains (1) summary
      pfam12847
      Location:59 → 173
      Methyltransf_18; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQJ8 Q9VQJ8

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