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    Vajk2 Vajk2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34811, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vajk2provided by FlyBase
    Official Full Name
    Vajk2provided by FlyBase
    Primary source
    FLYBASE:FBgn0032538
    Locus tag
    Dmel_CG16885
    See related
    AllianceGenome:FB:FBgn0032538
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16885; CG18634; Dmel\CG16885; vajk-2
    Summary
    Predicted to enable chitin binding activity. Predicted to be a structural constituent of chitin-based cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic epipharynx; embryonic head epidermis; and embryonic hypopharynx. Orthologous to human ZNF512B (zinc finger protein 512B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vajk2 in Genome Data Viewer
    Location:
    34E4-34E4; 2-50 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13932559..13934692, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13932559..13934692, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ance-3 Neighboring gene Vajk1 Neighboring gene uncharacterized protein Neighboring gene Vajk3 Neighboring gene Nimrod A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. Cinege G, et al. Insect Biochem Mol Biol, 2017 Aug. PMID 28633893
    2. Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis. Kondo T, et al. Science, 2010 Jul 16. PMID 20647469
    3. SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of Drosophila. Rizzo NP, et al. Development, 2017 Jun 15. PMID 28506986, Free PMC Article
    4. Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation in Drosophila. Chow CY, et al. Hum Mol Genet, 2016 Feb 15. PMID 26662796, Free PMC Article
    5. Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. Pasquier C, et al. Life Sci Alliance, 2022 Feb. PMID 34844981, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables structural constituent of chitin-based cuticle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Vajk2
    Names
    CG16885-PA
    Vajk2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      13932559..13934692 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135845.4 → NP_609689.3  Vajk2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609689.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZM2, Q9VJV0
      Related
      FBpp0080135
      Conserved Domains (1) summary
      pfam07489
      Location:32 → 97
      Tir_receptor_C; Translocated intimin receptor (Tir) C-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZM2 Q8SZM2

    Gene LinkOut

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