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    Dbx Dbx [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38254, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dbxprovided by FlyBase
    Official Full Name
    Dbxprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261723
    Locus tag
    Dmel_CG42234
    See related
    AllianceGenome:FB:FBgn0261723
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12361; CG13925; CG42234; dbx; DBX; dDbx; Dmel\CG42234
    Old locus tag
    Dmel_CG12361; Dmel_CG13925
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in axon guidance and neuron fate commitment. Is expressed in NB3-2 lineage neurons and segmentally-repeated neuroblast. Orthologous to human DBX1 (developing brain homeobox 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dbx in Genome Data Viewer
    Location:
    62B10-62B11; 3-1.0 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1921307..1933602)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1921307..1933602)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Tetraspan membrane protein in hair cell stereocilia Neighboring gene debris buster Neighboring gene transfer RNA:Cysteine-GCA 2-1 Neighboring gene long non-coding RNA:CR45826 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44536 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuron fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Dbx
    Names
    CG42234-PC
    Dbx-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1921307..1933602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139420.4 → NP_647677.2  Dbx [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647677.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W064
      Conserved Domains (1) summary
      pfam00046
      Location:437 → 490
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W064 Q9W064

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