U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG8562 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38828, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG8562provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035779
    Locus tag
    Dmel_CG8562
    See related
    AllianceGenome:FB:FBgn0035779
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT15463; Dmel\CG8562
    Summary
    Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in amnioserosa; embryonic midgut chamber; embryonic/larval midgut interstitial cell; and midgut interstitial cell primordium. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG8562 in Genome Data Viewer
    Location:
    65F11-65F11; 3-20 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7398285..7399912)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7391385..7393012)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genomic response to selection for postponed senescence in Drosophila. Wilson RH, et al. Mech Ageing Dev, 2013 Mar. PMID 23262286, Free PMC Article
    2. Fitness Analysis and Transcriptome Profiling Following Repeated Mild Heat Stress of Varying Frequency in Drosophilamelanogaster Females. Gruntenko NE, et al. Biology (Basel), 2021 Dec 14. PMID 34943239, Free PMC Article
    3. Age-Related Changes of Gene Expression Profiles in Drosophila. Bordet G, et al. Genes (Basel), 2021 Dec 14. PMID 34946931, Free PMC Article
    4. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. De Gregorio E, et al. EMBO J, 2002 Jun 3. PMID 12032070, Free PMC Article
    5. Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior. Ceriani MF, et al. J Neurosci, 2002 Nov 1. PMID 12417656, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG8562-PA
    NP_648118.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7398285..7399912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139861.3 → NP_648118.1  uncharacterized protein Dmel_CG8562 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648118.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXR8, Q9VS66
      Related
      FBpp0076564
      Conserved Domains (2) summary
      cd03860
      Location:124 → 420
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
      pfam02244
      Location:30 → 99
      Propep_M14; Carboxypeptidase activation peptide
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXR8 Q8SXR8
    Q9VS66 Q9VS66

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous