Trmt112 tRNA methyltransferase subunit 11-2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Trmt112provided by FlyBase
Official Full Name: tRNA methyltransferase subunit 11-2provided by FlyBase
Primary source: FLYBASE:FBgn0037061
Locus tag: Dmel_CG12975
See related: AllianceGenome:FB:FBgn0037061
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RE57810; CG12975; Dmel\CG12975
Summary: Predicted to enable tRNA methyltransferase activator activity. Involved in rRNA methylation. Predicted to be part of tRNA (m2G10) methyltransferase complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human TRMT112 (tRNA methyltransferase activator subunit 11-2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (21215995..21216839, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (21209095..21209939, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables tRNA methyltransferase activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in maturation of LSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
involved_in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA methylation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of tRNA (m2G10) methyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of tRNA (m2G10) methyltransferase complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain