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    Or85a Odorant receptor 85a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40991, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or85aprovided by FlyBase
    Official Full Name
    Odorant receptor 85aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037576
    Locus tag
    Dmel_CG7454
    See related
    AllianceGenome:FB:FBgn0037576
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    85a; 85A.4; CG7454; Dmel\CG7454; DmOr85a; DmOR85A; DOR31; Or-85a; or85a; OR85a
    Summary
    Enables ionotropic olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Located in plasma membrane. Is expressed in adult olfactory receptor neuron Or85a; antennal basiconic sensillum ab2; and antennal lobe glomerulus DM5. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

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    See Or85a in Genome Data Viewer
    Location:
    84F11-84F11; 3-48 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8321747..8323054)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4147469..4148776)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45215 Neighboring gene Coenzyme Q biosynthesis protein 2 Neighboring gene Copper transporter 1B Neighboring gene Pox meso Neighboring gene uncharacterized protein Neighboring gene Cytochrome c oxidase subunit 7A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Measuring activity in olfactory receptor neurons in Drosophila: Focus on spike amplitude. Martin F, et al. J Insect Physiol, 2016 Dec. PMID 27614176
    2. The Evolution of Olfactory Gene Families in Drosophila and the Genomic Basis of chemical-Ecological Adaptation in Drosophila suzukii. Ramasamy S, et al. Genome Biol Evol, 2016 Aug 16. PMID 27435796, Free PMC Article
    3. Odorant reception in the malaria mosquito Anopheles gambiae. Carey AF, et al. Nature, 2010 Mar 4. PMID 20130575, Free PMC Article
    4. Subunit contributions to insect olfactory receptor function: channel block and odorant recognition. Nichols AS, et al. Chem Senses, 2011 Nov. PMID 21677030, Free PMC Article
    5. Sensory processing during sleep in Drosophila melanogaster. French AS, et al. Nature, 2021 Oct. PMID 34588694

    See all (80) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ionotropic olfactory receptor activity HDA PubMed 
    enables odorant binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of smell HDA PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in dendrite membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    odorant receptor 85a
    Names
    CG7454-PA
    Or85a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8321747..8323054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079553.1 → NP_524277.1  odorant receptor 85a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524277.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VHS4
      UniProtKB/TrEMBL
      D7F910, D7F911, D7F913
      Related
      FBpp0081326, FBtr0081836
      Conserved Domains (1) summary
      pfam02949
      Location:77 → 379
      7tm_6; 7tm Odorant receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHS4.1 Q9VHS4

    Gene LinkOut

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    Other Literature Sources
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