Task6 TWIK-related acid-sensitive K[+] channel 6 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Task6provided by FlyBase
Official Full Name: TWIK-related acid-sensitive K[+] channel 6provided by FlyBase
Primary source: FLYBASE:FBgn0038165
Locus tag: Dmel_CG9637
See related: AllianceGenome:FB:FBgn0038165
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0109301.11; anon-WO0109301.53; anon-WO0109301.54; anon-WO0109301.55; anon-WO0109301.56; anon-WO0109301.57; anon-WO0109301.58; anon-WO0109301.59; anon-WO0109301.60; CG9637; Dmel\CG9637; dmTASK6; dTASK-6; K2P-TASK6; TASK-6; TASK6
Summary: Enables potassium channel activity and protein heterodimerization activity. Involved in potassium ion transmembrane transport. Located in membrane. Is expressed in several structures, including adult brain cell body rind; anterior-posterior subdivision of organism; and cell body rind of adult antennal lobe. Human ortholog(s) of this gene implicated in Birk-Barel syndrome and primary pulmonary hypertension. Orthologous to several human genes including KCNK9 (potassium two pore domain channel subfamily K member 9). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (13667046..13674542, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (9492768..9500264, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables outward rectifier potassium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables potassium channel activity	IDA Inferred from Direct Assay more info	PubMed
enables potassium channel activity	IEA Inferred from Electronic Annotation more info
enables potassium ion leak channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in potassium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in potassium ion transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in potassium ion transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: CG9637-PC; CG9637-PD; CG9637-PE; CG9637-PF; Task6-PC; Task6-PD; Task6-PE; Task6-PF

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The following sections contain reference sequences that belong to a specific genome build. Explain