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    CG3815 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31571, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3815provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029861
    Locus tag
    Dmel_CG3815
    See related
    AllianceGenome:FB:FBgn0029861
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3815; Pf1; PF1
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Part of Sin3-type complex. Is expressed in organism. Orthologous to human PHF12 (PHD finger protein 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3815 in Genome Data Viewer
    Location:
    5E6-5E7; 1-16 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6295389..6298970)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6189422..6193003)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene mulder Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3. Lee N, et al. Mol Cell Biol, 2009 Mar. PMID 19114561, Free PMC Article
    2. Cumulative contributions of weak DNA determinants to targeting the Drosophila dosage compensation complex. Gilfillan GD, et al. Nucleic Acids Res, 2007. PMID 17483514, Free PMC Article
    3. Systematic Analysis of SIN3 Histone Modifying Complex Components During Development. Barnes VL, et al. Sci Rep, 2018 Nov 19. PMID 30451916, Free PMC Article
    4. Drosophila SIN3 isoforms interact with distinct proteins and have unique biological functions. Spain MM, et al. J Biol Chem, 2010 Aug 27. PMID 20566628, Free PMC Article
    5. The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules. Zhang W, et al. J Mol Biol, 2016 Jul 17. PMID 27117189, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Sin3-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Sin3-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3815-PA
    PF1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      6295389..6298970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132083.4 → NP_572311.1  uncharacterized protein Dmel_CG3815 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572311.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T0U1, Q9W410
      Related
      FBpp0070864
      Conserved Domains (5) summary
      cd00060
      Location:732 → 765
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd15533
      Location:55 → 99
      PHD1_PHF12; PHD finger 1 found in PHD finger protein 12 (PHF12)
      cd15534
      Location:259 → 303
      PHD2_PHF12_Rco1; PHD finger 2 found in PHD finger protein 12 (PHF12), yeast Rco1, and similar proteins
      pfam16737
      Location:175 → 211
      PHF12_MRG_bd; PHD finger protein 12 MRG binding domain
      cl02608
      Location:75 → 198
      BAH; BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W410 Q9W410

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