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    bnb bangles and beads [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32872, updated on 17-Dec-2024

    Summary

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    Official Symbol
    bnbprovided by FlyBase
    Official Full Name
    bangles and beadsprovided by FlyBase
    Primary source
    FLYBASE:FBgn0001090
    Locus tag
    Dmel_CG7088
    See related
    AllianceGenome:FB:FBgn0001090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Bnb; CG7088; Dmel\CG7088; gap43; Gap43; GAP43
    Summary
    Involved in gliogenesis. Is expressed in several structures, including anlage in statu nascendi; epidermis; extraembryonic structure; head epidermis primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See bnb in Genome Data Viewer
    Location:
    17D6-17D6; 1-60 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18794246..18797687, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (18688279..18691720, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene S6 Kinase Like Neighboring gene Autophagy-related 101 Neighboring gene antisense RNA:CR44841 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Drosophila gene expressed in the embryonic CNS shares one conserved domain with the mammalian GAP-43. Ng SC, et al. Development, 1989 Mar. PMID 2693037
    2. Cellular defects resulting from disease-related myosin II mutations in Drosophila. Kasza KE, et al. Proc Natl Acad Sci U S A, 2019 Oct 29. PMID 31615886, Free PMC Article
    3. Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation. Baltruschat L, et al. Cell Rep, 2021 Mar 16. PMID 33730583, Free PMC Article
    4. A dynamic microtubule cytoskeleton directs medial actomyosin function during tube formation. Booth AJR, et al. Dev Cell, 2014 Jun 9. PMID 24914560, Free PMC Article
    5. Anisotropy links cell shapes to tissue flow during convergent extension. Wang X, et al. Proc Natl Acad Sci U S A, 2020 Jun 16. PMID 32467168, Free PMC Article

    See all (71) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in gliogenesis IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    bangles and beads
    Names
    Bangles-n-beads
    CG7088-PA
    CG7088-PB
    CG7088-PC
    CG7088-PD
    bnb-PA
    bnb-PB
    bnb-PC
    bnb-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18794246..18797687 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167634.3 → NP_728202.1  bangles and beads, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728202.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V4R4, P29746, Q0KHQ7, Q9VWQ0
      Related
      FBpp0074427
      Conserved Domains (1) summary
      PTZ00121
      Location:35 → 423
      PTZ00121; MAEBL; Provisional

    2. NM_078682.4 → NP_523406.1  bangles and beads, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523406.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V4R4, P29746, Q0KHQ7, Q9VWQ0
      Related
      FBpp0074428
      Conserved Domains (1) summary
      PTZ00121
      Location:35 → 423
      PTZ00121; MAEBL; Provisional

    3. NM_167633.2 → NP_728201.1  bangles and beads, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728201.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V4R4, P29746, Q0KHQ7, Q9VWQ0
      Related
      FBpp0074429
      Conserved Domains (1) summary
      PTZ00121
      Location:35 → 423
      PTZ00121; MAEBL; Provisional

    4. NM_167635.3 → NP_728203.1  bangles and beads, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728203.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V4R4, P29746, Q0KHQ7, Q9VWQ0
      Related
      FBpp0074430
      Conserved Domains (1) summary
      PTZ00121
      Location:35 → 423
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P29746.1 P29746

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