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    CG7137 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37204, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG7137provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034422
    Locus tag
    Dmel_CG7137
    See related
    AllianceGenome:FB:FBgn0034422
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7137
    Summary
    Predicted to enable methylated histone binding activity and rRNA (adenine) methyltransferase activity. Predicted to be involved in cellular response to glucose starvation; rDNA heterochromatin formation; and regulation of transcription by glucose. Predicted to be located in rDNA heterochromatin. Predicted to be part of chromatin silencing complex. Predicted to be active in nucleolus. Is expressed in adult head. Orthologous to human RRP8 (ribosomal RNA processing 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG7137 in Genome Data Viewer
    Location:
    56C4-56C4; 2-88 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19227344..19228613)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15114849..15116118)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene happyhour Neighboring gene coracle Neighboring gene windbeutel

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables rRNA (adenine) methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to glucose starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in rDNA heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in rDNA heterochromatin formation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of transcription by glucose IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of chromatin silencing complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of chromatin silencing complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in rDNA heterochromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in rDNA heterochromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG7137-PA
    gene 3
    NP_611400.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19227344..19228613
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137556.4NP_611400.1  uncharacterized protein Dmel_CG7137 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611400.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7K2B0
      Related
      FBpp0085693
      Conserved Domains (1) summary
      cl17173
      Location:150358
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...