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    CG8833 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39535, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8833provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036386
    Locus tag
    Dmel_CG8833
    See related
    AllianceGenome:FB:FBgn0036386
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8833; GPTC1
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in organism. Orthologous to human GPATCH1 (G-patch domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8833 in Genome Data Viewer
    Location:
    70C5-70C5; 3-41 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13925882..13929000, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13918982..13922100, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene dyschronic Neighboring gene uncharacterized protein Neighboring gene Ral guanine nucleotide dissociation stimulator-like Neighboring gene Dynactin 1, p150 subunit Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control. Siller KH, et al. Mol Biol Cell, 2005 Nov. PMID 16107559, Free PMC Article
    2. A Ral guanine exchange factor-Ral pathway is conserved in Drosophila melanogaster and sheds new light on the connectivity of the Ral, Ras, and Rap pathways. Mirey G, et al. Mol Cell Biol, 2003 Feb. PMID 12529414, Free PMC Article
    3. A neurogenetic mechanism of experience-dependent suppression of aggression. Ishii K, et al. Sci Adv, 2022 Sep 9. PMID 36070378, Free PMC Article
    4. A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage. Schulz C, et al. Genetics, 2004 Jun. PMID 15238523, Free PMC Article
    5. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8833-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      13925882..13929000 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140412.2 → NP_648669.1  uncharacterized protein Dmel_CG8833 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648669.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C1C3H2, Q95RM7, Q9VUA0
      Related
      FBpp0075534
      Conserved Domains (2) summary
      pfam01585
      Location:154 → 201
      G-patch; G-patch domain
      pfam07713
      Location:27 → 112
      DUF1604; Protein of unknown function (DUF1604)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VUA0.1 Q9VUA0

    Gene LinkOut

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