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    CG11836 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43007, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11836provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039272
    Locus tag
    Dmel_CG11836
    See related
    AllianceGenome:FB:FBgn0039272
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11836; SP23
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in several structures, including embryonic dorsal epidermis; embryonic head epidermis; embryonic hypopharynx; embryonic ventral epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11836 in Genome Data Viewer
    Location:
    96B20-96B20; 3-86 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25071126..25072712)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20896848..20898434)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Poly-glutamine tract binding protein 1 Neighboring gene Catalytic subunit 3B of the oligosaccharyltransferase complex Neighboring gene uncharacterized protein Neighboring gene shams Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Negative regulation of notch signaling by xylose. Lee TV, et al. PLoS Genet, 2013 Jun. PMID 23754965, Free PMC Article
    2. FlyXCDB-A Resource for Drosophila Cell Surface and Secreted Proteins and Their Extracellular Domains. Pei J, et al. J Mol Biol, 2018 Sep 14. PMID 29890119
    3. Meta-Analysis of Grainyhead-Like Dependent Transcriptional Networks: A Roadmap for Identifying Novel Conserved Genetic Pathways. Mathiyalagan N, et al. Genes (Basel), 2019 Oct 31. PMID 31683705, Free PMC Article
    4. A genome-wide analysis of immune responses in Drosophila. Irving P, et al. Proc Natl Acad Sci U S A, 2001 Dec 18. PMID 11742098, Free PMC Article
    5. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11836-PA
    CG11836-PB
    CG11836-PC
    CG11836-PE
    CG11836-PF
    CG11836-PG
    CG11836-PI
    CG11836-PJ
    NP_001097910.1
    NP_001163718.3
    • non-AUG (AUU) translation initiation
    NP_001189290.1
    NP_001189291.1
    NP_001189292.1
    NP_001356925.1
    NP_651333.1
    NP_733078.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25071126..25072712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001369964.1 → NP_001356925.1  uncharacterized protein Dmel_CG11836, isoform J [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K1E7
      Conserved Domains (1) summary
      cd00190
      Location:97 → 325
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    2. NM_170199.2 → NP_733078.1  uncharacterized protein Dmel_CG11836, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733078.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBY4
      Related
      FBpp0084142
      Conserved Domains (2) summary
      smart00020
      Location:1 → 212
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:1 → 215
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    3. NM_143076.5 → NP_651333.1  uncharacterized protein Dmel_CG11836, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651333.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBY4
      Related
      FBpp0084143
      Conserved Domains (2) summary
      smart00020
      Location:1 → 212
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:1 → 215
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    4. NM_001104440.5 → NP_001097910.1  uncharacterized protein Dmel_CG11836, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097910.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBY4
      Conserved Domains (2) summary
      smart00020
      Location:1 → 212
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:1 → 215
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    5. NM_001202361.3 → NP_001189290.1  uncharacterized protein Dmel_CG11836, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189290.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBY4
      Conserved Domains (2) summary
      smart00020
      Location:1 → 212
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:1 → 215
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    6. NM_001170247.4 → NP_001163718.3  uncharacterized protein Dmel_CG11836, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163718.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIW3
      Conserved Domains (2) summary
      smart00020
      Location:44 → 270
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:45 → 273
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    7. NM_001202363.3 → NP_001189292.1  uncharacterized protein Dmel_CG11836, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189292.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBY4
      Conserved Domains (2) summary
      smart00020
      Location:1 → 212
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:1 → 215
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    8. NM_001202362.3 → NP_001189291.1  uncharacterized protein Dmel_CG11836, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189291.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VBY4
      Conserved Domains (2) summary
      smart00020
      Location:1 → 212
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:1 → 215
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A4D6K1E7 A0A4D6K1E7
    E1JIW3 E1JIW3
    Q9VBY4 Q9VBY4

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