TfIIFalpha Transcription factor IIFalpha [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: TfIIFalphaprovided by FlyBase
Official Full Name: Transcription factor IIFalphaprovided by FlyBase
Primary source: FLYBASE:FBgn0010282
Locus tag: Dmel_CG10281
See related: AllianceGenome:FB:FBgn0010282
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 154355_at; CG10281; Dmel\CG10281; DmTFIIF; F5a; TfIIF; TFIIF; TFIIF-L; TFIIFa; TFIIFalpha
Summary: Enables TFIIF-class transcription factor complex binding activity. Involved in transcription elongation by RNA polymerase II and transcription initiation at RNA polymerase II promoter. Located in nucleus. Part of transcription factor TFIIF complex. Is expressed in several structures, including anlage in statu nascendi; embryonic/larval midgut primordium; endoderm anlage; gut section; and mesoderm. Orthologous to human GTF2F1 (general transcription factor IIF subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (6380467..6382604)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (2206189..2208326)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II general transcription initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables TFIIF-class transcription factor complex binding	IBA Inferred from Biological aspect of Ancestor more info
enables TFIIF-class transcription factor complex binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription elongation by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription initiation at RNA polymerase II promoter	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription initiation at RNA polymerase II promoter	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info
involved_in transcription initiation at RNA polymerase II promoter	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIF complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIIF complex	IDA Inferred from Direct Assay more info	PubMed
part_of transcription factor TFIIF complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: CG10281-PA; TFIIF large subunit; TfIIFalpha-PA; factor 5; factor 5a; large subunit of transcription factor 5

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The following sections contain reference sequences that belong to a specific genome build. Explain