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    CG15118 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37199, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15118provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034418
    Locus tag
    Dmel_CG15118
    See related
    AllianceGenome:FB:FBgn0034418
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:fe1H12; Dmel\CG15118
    Summary
    Located in cytoplasm. Is expressed in several structures, including Bolwig organ; adult head; embryonic anal pad; embryonic hindgut; and ganglia. Orthologous to several human genes including ANKRD13B (ankyrin repeat domain 13B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15118 in Genome Data Viewer
    Location:
    56B5-56B5; 2-88 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19133727..19137169, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15021232..15024674, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene brother of tout-velu Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43399 Neighboring gene enabled

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems. Hofmann K, et al. Trends Biochem Sci, 2001 Jun. PMID 11406394
    2. A functional misexpression screen uncovers a role for enabled in progressive neurodegeneration. Rezával C, et al. PLoS One, 2008 Oct 8. PMID 18841196, Free PMC Article
    3. Single-base pair differences in a shared motif determine differential Rhodopsin expression. Rister J, et al. Science, 2015 Dec 4. PMID 26785491, Free PMC Article
    4. Genetic and behavioral analysis of natural variation in Drosophila melanogaster pupation position. Riedl CA, et al. Fly (Austin), 2007 Jan-Feb. PMID 18690058
    5. Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10. Lee SY, et al. Cell Mol Life Sci, 2014 Jul. PMID 24292889, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15118-PA
    CG15118-PB
    CG15118-PD
    CG15118-PE
    anon-fast-evolving-1H12

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19133727..19137169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166325.2 → NP_725852.1  uncharacterized protein Dmel_CG15118, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725852.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4M9, Q8IGB6
      Related
      FBpp0085774
      Conserved Domains (5) summary
      cd00204
      Location:10 → 94
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam11904
      Location:155 → 497
      GPCR_chapero_1; GPCR-chaperone
      pfam12796
      Location:13 → 94
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:12 → 38
      ANK; ANK repeat [structural motif]
      cl00057
      Location:558 → 627
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    2. NM_137552.3 → NP_611396.1  uncharacterized protein Dmel_CG15118, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611396.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K4M9, Q8IGB6
      Related
      FBpp0085775
      Conserved Domains (5) summary
      cd00204
      Location:10 → 94
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam11904
      Location:155 → 497
      GPCR_chapero_1; GPCR-chaperone
      pfam12796
      Location:13 → 94
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:12 → 38
      ANK; ANK repeat [structural motif]
      cl00057
      Location:558 → 627
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    3. NM_001103904.2 → NP_001097374.1  uncharacterized protein Dmel_CG15118, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097374.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYI9, Q8IGB6
      Conserved Domains (4) summary
      cd00204
      Location:10 → 94
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam11904
      Location:155 → 497
      GPCR_chapero_1; GPCR-chaperone
      pfam12796
      Location:13 → 94
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:12 → 38
      ANK; ANK repeat [structural motif]

    4. NM_166327.2 → NP_725854.1  uncharacterized protein Dmel_CG15118, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725854.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBH1, Q8IGB6
      Related
      FBpp0085776
      Conserved Domains (3) summary
      pfam11904
      Location:110 → 452
      GPCR_chapero_1; GPCR-chaperone
      pfam12796
      Location:1 → 49
      Ank_2; Ankyrin repeats (3 copies)
      cl00057
      Location:513 → 582
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBH1 A1ZBH1
    A8DYI9 A8DYI9
    Q7K4M9 Q7K4M9
    Q8IGB6 Q8IGB6

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