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    CG4293 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31001, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4293provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024983
    Locus tag
    Dmel_CG4293
    See related
    AllianceGenome:FB:FBgn0024983
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    154711_at; Dmel\CG4293; EG:65F1.1
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be active in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and membrane. Is expressed in adult head; embryonic/larval salivary gland; embryonic/larval salivary gland body; organism; and salivary gland body primordium. Orthologous to human ERGIC2 (ERGIC and golgi 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4293 in Genome Data Viewer
    Location:
    1B8-1B9; 1-0 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (527941..530291, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (421974..424324, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44892 Neighboring gene silver Neighboring gene elav noncoding regulatory RNA Neighboring gene embryonic lethal abnormal vision Neighboring gene arginase Neighboring gene beta amyloid protein precursor-like Neighboring gene mir-4960 stem loop Neighboring gene ventral nervous system defective Neighboring gene split discs

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization. Smith ST, et al. Dev Biol, 2009 Apr 15. PMID 19210964, Free PMC Article
    2. Microarray analysis of immune challenged Drosophila hemocytes. Johansson KC, et al. Exp Cell Res, 2005 Apr 15. PMID 15777795
    3. RNAseq analysis of the drug jian-yan-ling (JYL) using both in vivo and in vitro models. Zhang X, et al. Heliyon, 2023 May. PMID 37251843, Free PMC Article
    4. A comparative genomic analysis of two distant diptera, the fruit fly, Drosophila melanogaster, and the malaria mosquito, Anopheles gambiae. Bolshakov VN, et al. Genome Res, 2002 Jan. PMID 11779831, Free PMC Article
    5. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in COPII-coated ER to Golgi transport vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4293-PA
    CG4293-PB
    CG4293-PC
    CG4293-PD
    CG4293-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      527941..530291 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038727.1 → NP_001033816.1  uncharacterized protein Dmel_CG4293, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76896
      Conserved Domains (2) summary
      pfam07970
      Location:200 → 349
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:19 → 104
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

    2. NM_001038728.3 → NP_001033817.1  uncharacterized protein Dmel_CG4293, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033817.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76896
      Conserved Domains (2) summary
      pfam07970
      Location:200 → 349
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:19 → 104
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

    3. NM_001272170.1 → NP_001259099.1  uncharacterized protein Dmel_CG4293, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259099.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PGB8
      Conserved Domains (2) summary
      pfam07970
      Location:200 → 347
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:19 → 104
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

    4. NM_130491.5 → NP_569847.1  uncharacterized protein Dmel_CG4293, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569847.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76896
      Related
      FBpp0070084
      Conserved Domains (2) summary
      pfam07970
      Location:200 → 349
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:19 → 104
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)

    5. NM_166847.4 → NP_726677.1  uncharacterized protein Dmel_CG4293, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726677.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76896
      Related
      FBpp0070085
      Conserved Domains (2) summary
      pfam07970
      Location:200 → 349
      COPIIcoated_ERV; Endoplasmic reticulum vesicle transporter
      pfam13850
      Location:19 → 104
      ERGIC_N; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PGB8 M9PGB8
    O76896 O76896

    Gene LinkOut

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