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    l(3)05822 lethal (3) 05822 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 47260, updated on 9-Dec-2024

    Summary

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    Official Symbol
    l(3)05822provided by FlyBase
    Official Full Name
    lethal (3) 05822provided by FlyBase
    Primary source
    FLYBASE:FBgn0010877
    Locus tag
    Dmel_CG7129
    See related
    AllianceGenome:FB:FBgn0010877
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    5822; CG7129; clot 3142; Dmel\CG7129; L(3)05822; l(3)5822; LD12970
    Summary
    Predicted to be involved in actin filament organization and cell migration. Is expressed in several structures, including anterior endoderm anlage; central brain primordium; dorsal epidermis primordium; ganglia; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See l(3)05822 in Genome Data Viewer
    Location:
    91A1-91A2; 3-63 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18288866..18298879, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14114588..14124601, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 1A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Dynein light chain 90F Neighboring gene RNA polymerase I subunit E

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. dtctex-1, the Drosophila melanogaster homolog of a putative murine t-complex distorter encoding a dynein light chain, is required for production of functional sperm. Caggese C, et al. Mol Genet Genomics, 2001 May. PMID 11405626
    2. The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation. Li MG, et al. Mol Biol Cell, 2004 Jul. PMID 15090621, Free PMC Article
    3. Bicaudal-C recruits CCR4-NOT deadenylase to target mRNAs and regulates oogenesis, cytoskeletal organization, and its own expression. Chicoine J, et al. Dev Cell, 2007 Nov. PMID 17981137
    4. Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599819, Free PMC Article
    5. Misexpression screen delineates novel genes controlling Drosophila lifespan. Paik D, et al. Mech Ageing Dev, 2012 May. PMID 22366109, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c18295863-18295675 mobile_element_type = transposon:INE-1{}4876

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    lethal (3) 05822
    Names
    CG7129-PA
    CG7129-PB
    CG7129-PC
    CG7129-PD
    l(3)05822-PA
    l(3)05822-PB
    l(3)05822-PC
    l(3)05822-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18288866..18298879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143794.3 → NP_652051.1  lethal (3) 05822, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652051.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE96
      Related
      FBpp0083016
      Conserved Domains (2) summary
      smart00326
      Location:452 → 506
      SH3; Src homology 3 domains
      cl17036
      Location:540 → 591
      SH3; Src Homology 3 domain superfamily

    2. NM_001275774.1 → NP_001262703.1  lethal (3) 05822, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262703.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE96
      Conserved Domains (2) summary
      smart00326
      Location:452 → 506
      SH3; Src homology 3 domains
      cl17036
      Location:540 → 591
      SH3; Src Homology 3 domain superfamily

    3. NM_001275773.1 → NP_001262702.1  lethal (3) 05822, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262702.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE96
      Conserved Domains (2) summary
      smart00326
      Location:452 → 506
      SH3; Src homology 3 domains
      cl17036
      Location:540 → 591
      SH3; Src Homology 3 domain superfamily

    4. NM_169802.2 → NP_732322.1  lethal (3) 05822, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732322.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VE96
      Related
      FBpp0083017
      Conserved Domains (2) summary
      smart00326
      Location:452 → 506
      SH3; Src homology 3 domains
      cl17036
      Location:540 → 591
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VE96 Q9VE96

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