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    IMT3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853501, updated on 9-Dec-2024

    Summary

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    Official Symbol
    IMT3
    Primary source
    SGD:S000006663
    Locus tag
    YNCJ0022C
    See related
    AllianceGenome:SGD:S000006663
    Gene type
    tRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables eukaryotic initiation factor eIF2 binding activity. Predicted to be involved in translational initiation. Part of eukaryotic 43S preinitiation complex and eukaryotic 48S preinitiation complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See IMT3 in Genome Data Viewer
    Location:
    chromosome: X
    Sequence:
    Chromosome: X; NC_001142.9 (517813..517884, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Nup85p Neighboring gene DNA polymerase delta subunit POL32 Neighboring gene Vps55p Neighboring gene Hsp70 family ATPase SSC1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An innovative protein expression system using RNA polymerase I for large-scale screening of high-nucleic-acid content Saccharomyces cerevisiae strains. Zeng D, et al. Microb Biotechnol, 2020 Nov. PMID 32854170, Free PMC Article
    2. A functional analysis of the repeated methionine initiator tRNA genes (IMT) in yeast. Byström AS, et al. Mol Gen Genet, 1989 Apr. PMID 2664453
    3. Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation. Kolitz SE, et al. RNA, 2009 Jan. PMID 19029312, Free PMC Article
    4. GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae. Calvo O, et al. Mol Cell Biol, 1999 Jun. PMID 10330157, Free PMC Article
    5. Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae. Iglesias-Gato D, et al. Genetics, 2011 Jan. PMID 20980241, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • Methionine initiator tRNA (tRNA-Met); predicted by tRNAscan-SE analysis; one of four initiator methionine tRNAs in yeast that are functional for translation

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables eukaryotic initiation factor eIF2 binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables triplet codon-amino acid adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables triplet codon-amino acid adaptor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational initiation IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of eukaryotic 43S preinitiation complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of eukaryotic 48S preinitiation complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

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