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    Rif1 Rap1 interacting factor 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246445, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rif1provided by FlyBase
    Official Full Name
    Rap1 interacting factor 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0050085
    Locus tag
    Dmel_CG30085
    See related
    AllianceGenome:FB:FBgn0050085
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD22218; CG30085; Dmel\CG30085; dRif1; XM_080537.1
    Summary
    Involved in embryonic development via the syncytial blastoderm; negative regulation of mitotic cell cycle phase transition; and regulation of DNA-templated DNA replication. Located in chromocenter and chromosome. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; head epidermis primordium; imaginal disc; and mesoderm. Orthologous to human RIF1 (replication timing regulatory factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Rif1 in Genome Data Viewer
    Location:
    52C8-52C8; 2-75 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (15864309..15869147, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (11751814..11756652, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene cGAS-like receptor 1 Neighboring gene Glycerophosphate oxidase 1 Neighboring gene slit Neighboring gene antisense RNA:CR46471 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44373

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromocenter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome, telomeric region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in chromosome, telomeric repeat region IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear replication fork IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    Rap1 interacting factor 1
    Names
    CG30085-PA
    Rap1 interacting factor 1 homolog
    Rif1-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      15864309..15869147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166120.2NP_725497.1  Rap1 interacting factor 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725497.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V5E2, Q9XZ34
      Related
      FBpp0086441
      Conserved Domains (3) summary
      pfam12231
      Location:110240
      Rif1_N; Rap1-interacting factor 1 N terminal
      cl25800
      Location:827920
      GGN; Gametogenetin
      cl26464
      Location:7051129
      Atrophin-1; Atrophin-1 family