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    CG30022 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36233, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG30022provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050022
    Locus tag
    Dmel_CG30022
    See related
    AllianceGenome:FB:FBgn0050022
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE56416; CG9026; Dmel\CG30022
    Summary
    Predicted to enable iron ion binding activity and sulfur dioxygenase activity. Predicted to be involved in glutathione metabolic process and hydrogen sulfide metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in mitochondrion. Used to study ethylmalonic encephalopathy. Human ortholog(s) of this gene implicated in ethylmalonic encephalopathy. Orthologous to human ETHE1 (ETHE1 persulfide dioxygenase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG30022 in Genome Data Viewer
    Location:
    47F8-47F8; 2-64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11387160..11388779, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7274665..7276284, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Tetraspanin 47F Neighboring gene Superoxide dismutase 3 Neighboring gene sprite Neighboring gene transfer RNA:Threonine-TGT 2-1 Neighboring gene transfer RNA:Threonine-TGT 2-2

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables iron ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables sulfur dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sulfur dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sulfur dioxygenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glutathione metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glutathione metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in hydrogen sulfide metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG30022-PB
    NP_725047.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11387160..11388779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165830.3NP_725047.2  uncharacterized protein Dmel_CG30022 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725047.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8L2, Q86PD3
      Conserved Domains (2) summary
      PLN02962
      Location:45277
      PLN02962; hydroxyacylglutathione hydrolase
      cd07724
      Location:49221
      POD-like_MBL-fold; ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain