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    CG30156 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246488, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30156provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050156
    Locus tag
    Dmel_CG30156
    See related
    AllianceGenome:FB:FBgn0050156
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT02529; BEST:GH05253; Dmel\CG30156
    Summary
    Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein and chaperone cofactor-dependent protein refolding. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30156 in Genome Data Viewer
    Location:
    42E1-42E1; 2-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6981446..6985712, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2868951..2873217, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene visceral mesodermal armadillo-repeats Neighboring gene long non-coding RNA:CR44170 Neighboring gene long non-coding RNA:CR44171 Neighboring gene uncharacterized protein Neighboring gene Tetraspanin 42Ea Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Autonomous transposons tune their sequences to ensure somatic suppression. Ilık İA, et al. Nature, 2024 Feb. PMID 38355802, Free PMC Article
    2. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
    3. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article
    4. Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells. Parkhitko AA, et al. PLoS Genet, 2021 Feb. PMID 33591981, Free PMC Article
    5. Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila. Perlegos AE, et al. Nat Commun, 2022 Sep 14. PMID 36104353, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to misfolded protein IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in chaperone cofactor-dependent protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30156-PA
    CG30156-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6981446..6985712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273823.2 → NP_001260752.1  uncharacterized protein Dmel_CG30156, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260752.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5U0V4, Q8IHG8
      Conserved Domains (2) summary
      pfam00226
      Location:96 → 157
      DnaJ; DnaJ domain
      pfam09320
      Location:237 → 334
      DUF1977; Domain of unknown function (DUF1977)

    2. NM_165500.1 → NP_724520.1  uncharacterized protein Dmel_CG30156, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724520.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5U0V4, Q8IHG8
      Related
      FBpp0085515, FBtr0086184
      Conserved Domains (2) summary
      pfam00226
      Location:96 → 157
      DnaJ; DnaJ domain
      pfam09320
      Location:237 → 334
      DUF1977; Domain of unknown function (DUF1977)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U0V4 Q5U0V4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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