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    eEF1delta eukaryotic translation elongation factor 1 delta [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eEF1deltaprovided by FlyBase
    Official Full Name
    eukaryotic translation elongation factor 1 deltaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032198
    Locus tag
    Dmel_CG4912
    See related
    AllianceGenome:FB:FBgn0032198
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4912; Dmel\CG4912; eEF1d; eEf1delta
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity and translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be part of eukaryotic translation elongation factor 1 complex. Predicted to be active in cytosol. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; gut section; mesoderm; and visceral mesoderm derivative. Orthologous to human EEF1D (eukaryotic translation elongation factor 1 delta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See eEF1delta in Genome Data Viewer
    Location:
    31B1-31B1; 2-40 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10232507..10234450)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10232507..10234450)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ovaries absent Neighboring gene methuselah-like 15 Neighboring gene maternal expression at 31B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Global analysis of positive and negative pre-mRNA splicing regulators in Drosophila. Blanchette M, et al. Genes Dev, 2005 Jun 1. PMID 15937219, Free PMC Article
    2. Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation. Zabidi MA, et al. Nature, 2015 Feb 26. PMID 25517091, Free PMC Article
    3. A Quantitative Proteomic Analysis of In Vitro Assembled Chromatin. Völker-Albert MC, et al. Mol Cell Proteomics, 2016 Mar. PMID 26811354, Free PMC Article
    4. Genome-wide assessment of AU-rich elements by the AREScore algorithm. Spasic M, et al. PLoS Genet, 2012 Jan. PMID 22242014, Free PMC Article
    5. Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. Olesnicky EC, et al. G3 (Bethesda), 2014 Feb 19. PMID 24347626, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation elongation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of eukaryotic translation elongation factor 1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic translation elongation factor 1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation elongation factor 1 delta
    Names
    CG4912-PA
    CG4912-PB
    eEF1delta-PA
    eEF1delta-PB
    eukaryotic translation elongation factor 1delta

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10232507..10234450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135517.4 → NP_609361.1  eukaryotic translation elongation factor 1 delta, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609361.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VL18, Q9VL19
      Related
      FBpp0079542
      Conserved Domains (2) summary
      cd00292
      Location:168 → 256
      EF1B; Elongation factor 1 beta (EF1B) guanine nucleotide exchange domain. EF1B catalyzes the exchange of GDP bound to the G-protein, EF1A, for GTP, an important step in the elongation cycle of the protein biosynthesis. EF1A binds to and delivers the aminoacyl ...
      pfam10587
      Location:134 → 156
      EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region

    2. NM_164895.3 → NP_723536.1  eukaryotic translation elongation factor 1 delta, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723536.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VL18
      Related
      FBpp0079541
      Conserved Domains (2) summary
      cd00292
      Location:141 → 229
      EF1B; Elongation factor 1 beta (EF1B) guanine nucleotide exchange domain. EF1B catalyzes the exchange of GDP bound to the G-protein, EF1A, for GTP, an important step in the elongation cycle of the protein biosynthesis. EF1A binds to and delivers the aminoacyl ...
      pfam10587
      Location:107 → 129
      EF-1_beta_acid; Eukaryotic elongation factor 1 beta central acidic region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VL18.1 Q9VL18

    Gene LinkOut

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