Rpn7 Regulatory particle non-ATPase 7 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Rpn7provided by FlyBase
Official Full Name: Regulatory particle non-ATPase 7provided by FlyBase
Primary source: FLYBASE:FBgn0028688
Locus tag: Dmel_CG5378
See related: AllianceGenome:FB:FBgn0028688
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 141231_at; anon-WO0172774.103; anon-WO0172774.106; CG5378; Dmel\CG5378; p42A; rpn7; S10a
Summary: Involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome regulatory particle. Is expressed in adult head and organism. Used to study neurodegenerative disease. Orthologous to human PSMD6 (proteasome 26S subunit, non-ATPase 6). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (22460662..22462054, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (18286384..18287776, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IC Inferred by Curator more info	PubMed
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of proteasome complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome regulatory particle	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome regulatory particle	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome regulatory particle	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of proteasome regulatory particle, lid subcomplex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain