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    CG5880 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43268, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5880provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039489
    Locus tag
    Dmel_CG5880
    See related
    AllianceGenome:FB:FBgn0039489
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5880
    Summary
    Predicted to enable protein-cysteine S-palmitoyltransferase activity. Located in Golgi apparatus. Is expressed in adult head; larval central nervous system; and organism. Orthologous to human ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5880 in Genome Data Viewer
    Location:
    97E2-97E2; 3-92 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27116745..27118532)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22942467..22944254)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A glial amino-acid transporter controls synapse strength and courtship in Drosophila. Grosjean Y, et al. Nat Neurosci, 2008 Jan. PMID 18066061, Free PMC Article
    2. Membrane targeting of inhibitory Smads through palmitoylation controls TGF-β/BMP signaling. Li W, et al. Proc Natl Acad Sci U S A, 2017 Dec 12. PMID 29180412, Free PMC Article
    3. The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes. Porcellato E, et al. PLoS One, 2022. PMID 35960718, Free PMC Article
    4. Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense. Deng Z, et al. J Genet Genomics, 2023 Dec. PMID 37343788
    5. The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. Bannan BA, et al. Fly (Austin), 2008 Jul-Aug. PMID 18719403, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-cysteine S-palmitoyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5880-PA
    NP_651539.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27116745..27118532
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143282.4 → NP_651539.3  uncharacterized protein Dmel_CG5880 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651539.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NHB0, Q9VB73
      Related
      FBpp0084478
      Conserved Domains (1) summary
      pfam01529
      Location:139 → 201
      zf-DHHC; DHHC palmitoyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95S28 Q95S28
    Q9VB73 Q9VB73

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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