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    Larp1b La ribonucleoprotein 1B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310348, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Larp1bprovided by RGD
    Official Full Name
    La ribonucleoprotein 1Bprovided by RGD
    Primary source
    RGD:1307509
    See related
    EnsemblRapid:ENSRNOG00000038366 AllianceGenome:RGD:1307509
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307509
    Summary
    Predicted to enable RNA binding activity. Orthologous to human LARP1B (La ribonucleoprotein 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 301.9), Testes (RPKM 268.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Larp1b in Genome Data Viewer
    Location:
    2q26
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (125860935..125897189)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (123936057..123969254)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (127845034..127876793)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 8 Neighboring gene FUN14 domain containing 2, pseudogene 1 Neighboring gene abhydrolase domain containing 18 Neighboring gene FUN14 domain containing 2B Neighboring gene La ribonucleoprotein 1B like Neighboring gene uncharacterized LOC134485903 Neighboring gene progesterone receptor membrane component 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic characterization of the human sperm nucleus. de Mateo S, et al. Proteomics, 2011 Jul. PMID 21630459
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    la-related protein 1B
    Names
    La ribonucleoprotein domain family, member 1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014036.4 → NP_001014058.1  la-related protein 1B isoform 2

      See identical proteins and their annotated locations for NP_001014058.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I5ZVS3, A6II43, F7FP27, Q66HE8
      Conserved Domains (1) summary
      cd08038
      Location:216 → 288
      LARP_2; La RNA-binding domain of La-related protein 2

    2. NM_001415051.1 → NP_001401980.1  la-related protein 1B isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I5ZWA7
      Related
      ENSRNOP00000083292.1, ENSRNOT00000110414.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      125860935..125897189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102244.2 → XP_038958172.1  la-related protein 1B isoform X1

      Conserved Domains (1) summary
      cl02755
      Location:418 → 473
      LAM; LA motif RNA-binding domain

    2. XM_039102245.2 → XP_038958173.1  la-related protein 1B isoform X2

    3. XM_039102247.2 → XP_038958175.1  la-related protein 1B isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZVS3, A6II43, F7FP27, Q66HE8
      Conserved Domains (1) summary
      cd08038
      Location:216 → 288
      LARP_2; La RNA-binding domain of La-related protein 2

    4. XM_039102246.2 → XP_038958174.1  la-related protein 1B isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZVS3, A6II43, F7FP27, Q66HE8
      Conserved Domains (1) summary
      cd08038
      Location:216 → 288
      LARP_2; La RNA-binding domain of La-related protein 2
    Nucleotide Protein Strain
    Heading Accession and Version

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