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    TVP15 Tvp15p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851677, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TVP15
    Official Full Name
    Tvp15p
    Primary source
    SGD:S000002507
    Locus tag
    YDR100W
    See related
    AllianceGenome:SGD:S000002507; FungiDB:YDR100W; VEuPathDB:YDR100W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in vesicle-mediated transport. Located in Golgi membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TVP15 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (655013..655444)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene gag-pol fusion protein Neighboring gene gag protein Neighboring gene 14-3-3 family protein BMH2 Neighboring gene putative hydrolase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The generational scalability of single-cell replicative aging. Liu P, et al. Sci Adv, 2018 Jan. PMID 29399632, Free PMC Article
    2. Profiling lipid-protein interactions using nonquenched fluorescent liposomal nanovesicles and proteome microarrays. Lu KY, et al. Mol Cell Proteomics, 2012 Nov. PMID 22843995, Free PMC Article
    3. The VINE complex is an endosomal VPS9-domain GEF and SNX-BAR coat. Shortill SP, et al. Elife, 2022 Aug 8. PMID 35938928, Free PMC Article
    4. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499
    5. Analysis of the TORC1 interactome reveals a spatially distinct function of TORC1 in mRNP complexes. Chang Y, et al. J Cell Biol, 2021 Apr 5. PMID 33566094, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Tvp proteins collectively assist in the effective maintenance/function of the late Golgi/endosomal compartments.
      Title: Tvp38, Tvp23, Tvp18 and Tvp15: novel membrane proteins in the Tlg2-containing Golgi/endosome compartments of Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tvp15p
    NP_010385.3
    • Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      655013..655444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180408.3 → NP_010385.3  TPA: Tvp15p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010385.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS87, Q03860
      UniProtKB/TrEMBL
      A6ZY64, B3LGH4, C7GQJ6, C8Z517, G2WAK4, N1PAD3
      Conserved Domains (1) summary
      pfam08507
      Location:6 → 132
      COPI_assoc; COPI associated protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03860.1

    Gene LinkOut

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