Zmym3 zinc finger MYM-type containing 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zmym3provided by RGD
Official Full Name: zinc finger MYM-type containing 3provided by RGD
Primary source: RGD:1564967
See related: EnsemblRapid:ENSRNOG00000003707 AllianceGenome:RGD:1564967
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human ZMYM3 (zinc finger MYM-type containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 147.7), Adrenal (RPKM 113.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq22

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (70568573..70584221, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (66528585..66544234, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (71298737..71313529, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Zmym3 (e-PCR), detects polymorphism
- UniSTS:502942

Zmym3 (e-PCR), detects polymorphism
- UniSTS:502943

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cytoskeleton organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell morphogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: zinc finger MYM-type protein 3

Names: zinc finger, MYM-type 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001040155.2 → NP_001035245.2 zinc finger MYM-type protein 3

See identical proteins and their annotated locations for NP_001035245.2

Status: PROVISIONAL

Source sequence(s)

CH473966

UniProtKB/TrEMBL

A0A8I6A895, A6IQB8, E9PTE5

Related

ENSRNOP00000088523.1, ENSRNOT00000076004.4

Conserved Domains (3) summary

smart00746
Location:314 → 350

TRASH; metallochaperone-like domain

pfam06467
Location:674 → 713

zf-FCS; MYM-type Zinc finger with FCS sequence motif

pfam12012
Location:1187 → 1353

DUF3504; Domain of unknown function (DUF3504)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086039.1 Reference GRCr8

Range

70568573..70584221 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001037785.1: Suppressed sequence

Description

NM_001037785.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.