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    HAL1 Hal1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856113, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HAL1
    Official Full Name
    Hal1p
    Primary source
    SGD:S000006209
    Locus tag
    YPR005C
    See related
    AllianceGenome:SGD:S000006209; FungiDB:YPR005C; VEuPathDB:YPR005C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in positive regulation of transcription by RNA polymerase II and response to salt stress. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See HAL1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (565787..566671, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Aim45p Neighboring gene methylisocitrate lyase ICL2 Neighboring gene Rec8p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast. Gaxiola R, et al. EMBO J, 1992 Sep. PMID 1505513, Free PMC Article
    2. Transfer of the yeast salt tolerance gene HAL1 to Cucumis melo L. cultivars and in vitro evaluation of salt tolerance. Bordas M, et al. Transgenic Res, 1997 Jan. PMID 9032977
    3. [Cloning of HAL1 gene and characterization for salt tolerance tomato]. Zhang Q, et al. Sheng Wu Gong Cheng Xue Bao, 2001 Nov. PMID 11910760
    4. Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. Hong ME, et al. J Biotechnol, 2010 Aug 20. PMID 20600383
    5. The Sko1p repressor and Gcn4p activator antagonistically modulate stress-regulated transcription in Saccharomyces cerevisiae. Pascual-Ahuir A, et al. Mol Cell Biol, 2001 Jan. PMID 11113177, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Hal1p
    NP_015330.1
    • Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      565787..566671 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184102.1 → NP_015330.1  TPA: Hal1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015330.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W416, Q01766
      UniProtKB/TrEMBL
      A6ZWQ0, C7GV30, N1NVJ1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q01766.1

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