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    IRC22 Irc22p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856717, updated on 9-Dec-2024

    Summary

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    Official Symbol
    IRC22
    Official Full Name
    Irc22p
    Primary source
    SGD:S000000727
    Locus tag
    YEL001C
    See related
    AllianceGenome:SGD:S000000727; FungiDB:YEL001C; VEuPathDB:YEL001C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See IRC22 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (150301..150978, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene tubulin-binding prefolding complex subunit GIM4 Neighboring gene dolichyl-diphosphooligosaccharide-protein glycotransferase Neighboring gene alpha-1,3-mannosyltransferase MNN1 Neighboring gene Nop16p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast Irc22 Is a Novel Dsk2-Interacting Protein that Is Involved in Salt Tolerance. Ishii T, et al. Cells, 2014 Mar 27. PMID 24709957, Free PMC Article
    2. Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. Alvaro D, et al. PLoS Genet, 2007 Dec. PMID 18085829, Free PMC Article
    3. A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase. Böttinger L, et al. Mol Biol Cell, 2013 Sep. PMID 23864706, Free PMC Article
    4. Heme, A Metabolic Sensor, Directly Regulates the Activity of the KDM4 Histone Demethylase Family and Their Interactions with Partner Proteins. Konduri PC, et al. Cells, 2020 Mar 22. PMID 32235736, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome V. Dietrich FS, et al. Nature, 1997 May 29. PMID 9169868, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Irc22p
    NP_010915.1
    • hypothetical protein; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      150301..150978 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178816.1 → NP_010915.1  TPA: Irc22p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010915.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZQU6, B3LS11, B5VHD1, C7GKH8, C8Z6Z8, D3DLP6, P40006, Q05243
      UniProtKB/TrEMBL
      G2WCN0, N1P7G1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40006.1

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