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    LDS2 Lds2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854110, updated on 9-Dec-2024

    Summary

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    Official Symbol
    LDS2
    Official Full Name
    Lds2p
    Primary source
    SGD:S000005407
    Locus tag
    YOL047C
    See related
    AllianceGenome:SGD:S000005407; FungiDB:YOL047C; VEuPathDB:YOL047C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore wall assembly. Located in ascospore wall; ascus lipid droplet; and prospore membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See LDS2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    2
    Sequence:
    Chromosome: XV; NC_001147.6 (241614..242747, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene glutathione synthase Neighboring gene Rrt8p Neighboring gene serine/threonine protein kinase PSK2 Neighboring gene Pex15p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In vitro reconstitution of the yeast spore wall dityrosine layer discloses the mechanism of its assembly. Bemena LD, et al. J Biol Chem, 2017 Sep 22. PMID 28794156, Free PMC Article
    2. Lipid droplet proteins, Lds1p, Lds2p, and Rrt8p, are implicated in membrane protein transport associated with ergosterol. Ueno K, et al. Biochem Biophys Res Commun, 2016 Jul 8. PMID 27216456
    3. A highly redundant gene network controls assembly of the outer spore wall in S. cerevisiae. Lin CP, et al. PLoS Genet, 2013. PMID 23966878, Free PMC Article
    4. A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast. Lam C, et al. Eukaryot Cell, 2014 Mar. PMID 24390141, Free PMC Article
    5. Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. She R, et al. Proc Natl Acad Sci U S A, 2017 Apr 4. PMID 28325876, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ascospore wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ascospore wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ascus lipid droplet IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in lipid droplet HDA PubMed 
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in prospore membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in prospore membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spore wall IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lds2p
    NP_014595.2
    • Protein Involved in spore wall assembly; localizes to lipid droplets found on or outside of the prospore membrane; shares similarity with Lds1p and Rrt8p, and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      241614..242747 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183301.1 → NP_014595.2  TPA: Lds2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014595.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W220, Q08218
      UniProtKB/TrEMBL
      B3LJ12, C7GK15, C8ZHR7, N1NY32
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08218.2

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