VPS17 retromer subunit VPS17 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: VPS17
Official Full Name: retromer subunit VPS17
Primary source: SGD:S000005658
Locus tag: YOR132W
See related: AllianceGenome:SGD:S000005658; FungiDB:YOR132W; VEuPathDB:YOR132W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: PEP21; VPT3
Summary: Enables phosphatidylinositol-3-phosphate binding activity. Contributes to protein transporter activity. Involved in retrograde transport, endosome to Golgi. Located in endosome. Part of retromer, tubulation complex. [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol-3-phosphate binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol-3-phosphate binding	IDA Inferred from Direct Assay more info	PubMed
enables phosphatidylinositol-3-phosphate binding	IEA Inferred from Electronic Annotation more info
contributes_to protein transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
contributes_to protein transporter activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in retrograde transport, endosome to Golgi	IBA Inferred from Biological aspect of Ancestor more info
involved_in retrograde transport, endosome to Golgi	IEA Inferred from Electronic Annotation more info
involved_in retrograde transport, endosome to Golgi	IPI Inferred from Physical Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in endomembrane system	IEA Inferred from Electronic Annotation more info
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in endosome	IPI Inferred from Physical Interaction more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of retromer complex	IEA Inferred from Electronic Annotation more info
part_of retromer complex	IMP Inferred from Mutant Phenotype more info	PubMed
part_of retromer complex	IPI Inferred from Physical Interaction more info	PubMed
part_of retromer, tubulation complex	IBA Inferred from Biological aspect of Ancestor more info
part_of retromer, tubulation complex	IPI Inferred from Physical Interaction more info	PubMed

NP_014775.3

Subunit of the membrane-associated retromer complex; essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation; required for recruiting the retromer complex to the endosome membranes

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The following sections contain reference sequences that belong to a specific genome build. Explain