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    RML2 mitochondrial 54S ribosomal protein RML2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856660, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RML2
    Official Full Name
    mitochondrial 54S ribosomal protein RML2
    Primary source
    SGD:S000000776
    Locus tag
    YEL050C
    See related
    AllianceGenome:SGD:S000000776; FungiDB:YEL050C; VEuPathDB:YEL050C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uL2m
    Summary
    A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL2 (mitochondrial ribosomal protein L2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RML2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (59670..60851, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Afg1p Neighboring gene H(+)-transporting V1 sector ATPase subunit D Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of ribosomal protein L2 in yeast mitochondria. Pan C, et al. J Biol Chem, 1997 Mar 28. PMID 9079633
    2. A mutation in the yeast mitochondrial ribosomal protein Rml2p is associated with a defect in catalase gene expression. Hagerman RA, et al. Mol Cell Biol Res Commun, 2001 Sep. PMID 11529680
    3. A yeast strain defective in oleic acid utilization has a mutation in the RML2 gene. Trotter PJ, et al. Biochim Biophys Acta, 1999 May 18. PMID 10320805
    4. Mitochondrial ribosomal proteins (MRPs) of yeast. Graack HR, et al. Biochem J, 1998 Feb 1. PMID 9445368, Free PMC Article
    5. Identification of novel genes involved in neutral lipid storage by quantitative trait loci analysis of Saccharomyces cerevisiae. Pačnik K, et al. BMC Genomics, 2021 Feb 9. PMID 33563210, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein RML2
    NP_010864.3
    • Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      59670..60851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178865.3 → NP_010864.3  TPA: mitochondrial 54S ribosomal protein RML2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010864.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLK0, P32611
      UniProtKB/TrEMBL
      A6ZQQ1, B3LRW7, B5VH87, C7GXD7, C8Z6U4, G2WCI4, N1P5H1
      Conserved Domains (1) summary
      COG0090
      Location:91 → 387
      RplB; Ribosomal protein L2 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32611.1

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