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    Gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [ Mus musculus (house mouse) ]

    Gene ID: 14699, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gngt1provided by MGI
    Official Full Name
    guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1provided by MGI
    Primary source
    MGI:MGI:109165
    See related
    Ensembl:ENSMUSG00000029663 AllianceGenome:MGI:109165
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gng1; G(y)1; Hg3g1
    Summary
    Predicted to enable G-protein beta-subunit binding activity and GTPase activity. Acts upstream of or within eye photoreceptor cell development; phototransduction; and protein localization. Predicted to be located in photoreceptor inner segment and photoreceptor outer segment. Predicted to be part of heterotrimeric G-protein complex. Is expressed in brain; retina; retina outer nuclear layer; and spleen. Orthologous to human GNGT1 (G protein subunit gamma transducin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gngt1 in Genome Data Viewer
    Location:
    6 A1; 6 1.81 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (3989082..3997441)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (3989082..3997436)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15005 Neighboring gene protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) pseudogene Neighboring gene STARR-seq mESC enhancer starr_15006 Neighboring gene tissue factor pathway inhibitor 2 Neighboring gene guanine nucleotide binding protein (G protein), gamma 11 Neighboring gene RIKEN cDNA 4930528H21 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (3)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta-subunit binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of heterotrimeric G-protein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in photoreceptor inner segment IEA
    Inferred from Electronic Annotation
    more info
     
    located_in photoreceptor inner segment ISO
    Inferred from Sequence Orthology
    more info
     
    located_in photoreceptor outer segment IEA
    Inferred from Electronic Annotation
    more info
     
    located_in photoreceptor outer segment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    guanine nucleotide-binding protein G(T) subunit gamma-T1
    Names
    guanine nucleotide binding protein (G protein), gamma 1 subunit
    heterotrimeric guanine nucleotide-binding protein 3g1
    transducin gamma chain

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010314.3NP_034444.1  guanine nucleotide-binding protein G(T) subunit gamma-T1

      See identical proteins and their annotated locations for NP_034444.1

      Status: VALIDATED

      Source sequence(s)
      AC022235, AK020903
      Consensus CDS
      CCDS39418.1
      UniProtKB/Swiss-Prot
      Q61012, Q9CR01
      Related
      ENSMUSP00000031673.6, ENSMUST00000031673.7
      Conserved Domains (1) summary
      smart00224
      Location:1274
      GGL; G protein gamma subunit-like motifs

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      3989082..3997441
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321388.3XP_017176877.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

      UniProtKB/Swiss-Prot
      Q61012, Q9CR01
      Conserved Domains (1) summary
      smart00224
      Location:1274
      GGL; G protein gamma subunit-like motifs
    2. XM_017321389.3XP_017176878.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

      UniProtKB/Swiss-Prot
      Q61012, Q9CR01
      Conserved Domains (1) summary
      smart00224
      Location:1274
      GGL; G protein gamma subunit-like motifs
    3. XM_006504986.3XP_006505049.1  guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1

      See identical proteins and their annotated locations for XP_006505049.1

      UniProtKB/Swiss-Prot
      Q61012, Q9CR01
      Conserved Domains (1) summary
      smart00224
      Location:1274
      GGL; G protein gamma subunit-like motifs